PDF(Pubmed)
Abstract：
BACKGROUND: Lumbar spinal manipulative therapy (SMT) is a common intervention used to treat low back pain (LBP); however, the exact neurophysiological mechanisms of SMT reducing pain measured through pain pressure threshold (PPT) have not been fully explored beyond an immediate timeframe (e.g., immediately or five-minutes following) referencing a control group. Therefore, the purpose of this study was to investigate the neurophysiological effects of lumbar SMT compared to deactivated ultrasound using PPT immediately following and 30-minutes following SMT.
METHODS: A longitudinal, randomized controlled trial design was conducted between September to October 2023. Fifty-five participants were randomized into a control group of deactivated ultrasound (n = 29) or treatment group of right sidelying lumbar SMT (n = 26). PPT, recorded at the right posterior superior iliac spine (PSIS), was documented for each participant in each group prior to intervention, immediately, and 30-minutes after. A repeated measures ANOVA, with a post-hoc Bonferroni adjustment, was used to assess within-group and between-group differences in PPT. The significance level was set at a < 0.05 a priori.
RESULTS: Statistically significant differences were found between the deactivated ultrasound and lumbar SMT groups immediately (p = .05) and 30-minutes (p = .02) following intervention. A significant difference in the lumbar SMT group was identified from baseline to immediately following (p < .001) and 30-minutes following (p < .001), but no differences between immediately following and 30-minutes following intervention (p = .10). The deactivated ultrasound group demonstrated a difference between baseline and immediately after intervention with a reduced PPT (p = .003), but no significant difference was found from baseline to 30-minutes (p = .11) or immediately after intervention to 30-minutes (p = 1.0).
CONCLUSIONS: A right sidelying lumbar manipulation increased PPT at the right PSIS immediately after that lasted to 30-minutes when compared to a deactivated ultrasound control group. Future studies should further explore beyond the immediate and short-term neurophysiological effects of lumbar SMT to validate these findings.
BACKGROUND: This study was retrospectively registered on 4 December 2023 in ClinicalTrials (database registration number NCT06156605).
METHODS: A longitudinal, randomized controlled trial design was conducted between September to October 2023. Fifty-five participants were randomized into a control group of deactivated ultrasound (n = 29) or treatment group of right sidelying lumbar SMT (n = 26). PPT, recorded at the right posterior superior iliac spine (PSIS), was documented for each participant in each group prior to intervention, immediately, and 30-minutes after. A repeated measures ANOVA, with a post-hoc Bonferroni adjustment, was used to assess within-group and between-group differences in PPT. The significance level was set at a < 0.05 a priori.
RESULTS: Statistically significant differences were found between the deactivated ultrasound and lumbar SMT groups immediately (p = .05) and 30-minutes (p = .02) following intervention. A significant difference in the lumbar SMT group was identified from baseline to immediately following (p < .001) and 30-minutes following (p < .001), but no differences between immediately following and 30-minutes following intervention (p = .10). The deactivated ultrasound group demonstrated a difference between baseline and immediately after intervention with a reduced PPT (p = .003), but no significant difference was found from baseline to 30-minutes (p = .11) or immediately after intervention to 30-minutes (p = 1.0).
CONCLUSIONS: A right sidelying lumbar manipulation increased PPT at the right PSIS immediately after that lasted to 30-minutes when compared to a deactivated ultrasound control group. Future studies should further explore beyond the immediate and short-term neurophysiological effects of lumbar SMT to validate these findings.
BACKGROUND: This study was retrospectively registered on 4 December 2023 in ClinicalTrials (database registration number NCT06156605).
摘要：
背景：腰椎手法治疗（SMT）是用于治疗下腰痛（LBP）的常用干预措施；然而，通过疼痛压力阈值（PPT）测量的SMT减轻疼痛的确切神经生理机制尚未在即时时间范围内得到充分探索（例如，立即或五分钟后）引用对照组。因此,这项研究的目的是研究腰椎SMT与停用超声相比的神经生理效应，SMT后立即和30分钟后使用PPT。
方法：纵向，随机对照试验设计于2023年9月至10月进行.55名参与者被随机分为停用超声的对照组（n=29）或右侧腰SMT的治疗组（n=26）。PPT,记录在右髂后上棘（PSIS），在干预前记录了每组中的每个参与者，立即,30分钟后.重复测量方差分析，通过事后的Bonferroni调整，用于评估PPT的组内和组间差异。显著性水平预先设定为<0.05。
结果：在介入后立即（p=.05）和30分钟（p=.02）停用的超声和腰椎SMT组之间发现了统计学上的显着差异。腰椎SMT组从基线到紧接着（p<.001）和30分钟后（p<.001）发现了显着差异，但干预后立即和干预后30分钟之间没有差异(p=.10)。停用的超声组显示出基线和干预后立即减少的PPT之间的差异（p=.003），但从基线到30分钟(p=.11)或干预后立即到30分钟(p=1.0)无显著差异.
结论：与停用的超声对照组相比，右侧侧腰椎操作在持续30分钟后立即增加了右侧PSIS的PPT。未来的研究应进一步探索腰椎SMT的直接和短期神经生理效应，以验证这些发现。
背景：这项研究于2023年12月4日在ClinicalTrials（数据库注册号NCT06156605）中进行了回顾性注册。
方法：纵向，随机对照试验设计于2023年9月至10月进行.55名参与者被随机分为停用超声的对照组（n=29）或右侧腰SMT的治疗组（n=26）。PPT,记录在右髂后上棘（PSIS），在干预前记录了每组中的每个参与者，立即,30分钟后.重复测量方差分析，通过事后的Bonferroni调整，用于评估PPT的组内和组间差异。显著性水平预先设定为<0.05。
结果：在介入后立即（p=.05）和30分钟（p=.02）停用的超声和腰椎SMT组之间发现了统计学上的显着差异。腰椎SMT组从基线到紧接着（p<.001）和30分钟后（p<.001）发现了显着差异，但干预后立即和干预后30分钟之间没有差异(p=.10)。停用的超声组显示出基线和干预后立即减少的PPT之间的差异（p=.003），但从基线到30分钟(p=.11)或干预后立即到30分钟(p=1.0)无显著差异.
结论：与停用的超声对照组相比，右侧侧腰椎操作在持续30分钟后立即增加了右侧PSIS的PPT。未来的研究应进一步探索腰椎SMT的直接和短期神经生理效应，以验证这些发现。
背景：这项研究于2023年12月4日在ClinicalTrials（数据库注册号NCT06156605）中进行了回顾性注册。
