PDF(Pubmed)
Abstract：
BACKGROUND: Although 5-aminolevulinic acid is useful for the photodynamic diagnosis of bladder tumors, it often causes severe intraoperative hypotension. We report a case of postoperative cardiac arrest in addition to severe intraoperative hypotension, probably owing to the use of 5-aminolevulinic acid.
METHODS: An 81-year-old Japanese man was scheduled to undergo transurethral resection of bladder tumor. The patient took 5-aminolevulinic acid orally 2 hours before entering the operating room. After the induction of anesthesia, his blood pressure decreased to 47/33 mmHg. The patient\'s hypotension did not improve even after noradrenaline was administered. After awakening from anesthesia, the patient\'s systolic blood pressure increased to approximately 100 mmHg, but approximately 5 hours after returning to the ward, cardiac arrest occurred for approximately 12 seconds.
CONCLUSIONS: We experienced a case of postoperative cardiac arrest in a patient, probably owing to the use of 5-aminolevulinic acid. Although the cause of cardiac arrest is unknown, perioperative hemodynamic management must be carefully performed in patients taking 5-aminolevulinic acid.
METHODS: An 81-year-old Japanese man was scheduled to undergo transurethral resection of bladder tumor. The patient took 5-aminolevulinic acid orally 2 hours before entering the operating room. After the induction of anesthesia, his blood pressure decreased to 47/33 mmHg. The patient\'s hypotension did not improve even after noradrenaline was administered. After awakening from anesthesia, the patient\'s systolic blood pressure increased to approximately 100 mmHg, but approximately 5 hours after returning to the ward, cardiac arrest occurred for approximately 12 seconds.
CONCLUSIONS: We experienced a case of postoperative cardiac arrest in a patient, probably owing to the use of 5-aminolevulinic acid. Although the cause of cardiac arrest is unknown, perioperative hemodynamic management must be carefully performed in patients taking 5-aminolevulinic acid.
摘要：
背景：尽管5-氨基乙酰丙酸可用于膀胱肿瘤的光动力诊断，它通常会导致严重的术中低血压。我们报告了一例术后心脏骤停以及严重的术中低血压，可能是由于使用了5-氨基乙酰丙酸。
方法：一名81岁的日本男子计划接受经尿道膀胱肿瘤切除术。患者在进入手术室前2小时口服5-氨基乙酰丙酸。麻醉诱导后,他的血压下降到47/33mmHg。即使服用去甲肾上腺素，患者的低血压也没有改善。麻醉苏醒后,患者的收缩压升高到约100mmHg，但回到病房大约5小时后,心脏骤停发生约12秒.
结论：我们经历了一例患者术后心脏骤停，可能是由于使用了5-氨基乙酰丙酸。虽然心脏骤停的原因不明,对于服用5-氨基乙酰丙酸的患者,必须谨慎进行围手术期的血流动力学管理.
方法：一名81岁的日本男子计划接受经尿道膀胱肿瘤切除术。患者在进入手术室前2小时口服5-氨基乙酰丙酸。麻醉诱导后,他的血压下降到47/33mmHg。即使服用去甲肾上腺素，患者的低血压也没有改善。麻醉苏醒后,患者的收缩压升高到约100mmHg，但回到病房大约5小时后,心脏骤停发生约12秒.
结论：我们经历了一例患者术后心脏骤停，可能是由于使用了5-氨基乙酰丙酸。虽然心脏骤停的原因不明,对于服用5-氨基乙酰丙酸的患者,必须谨慎进行围手术期的血流动力学管理.
