{Reference Type}: Case Reports
{Title}: Severe hypotension and postoperative cardiac arrest caused by 5-aminolevulinic acid: a case report.
{Author}: Miyazaki T;Taguchi S;Obata N;Mizobuchi S;
{Journal}: J Med Case Rep
{Volume}: 18
{Issue}: 1
{Year}: 2024 May 30
暂无{DOI}: 10.1186/s13256-024-04589-x
{Abstract}: <B>BACKGROUND: </B>Although 5-aminolevulinic acid is useful for the photodynamic diagnosis of bladder tumors, it often causes severe intraoperative hypotension. We report a case of postoperative cardiac arrest in addition to severe intraoperative hypotension, probably owing to the use of 5-aminolevulinic acid.<BR><B>METHODS: </B>An 81-year-old Japanese man was scheduled to undergo transurethral resection of bladder tumor. The patient took 5-aminolevulinic acid orally 2 hours before entering the operating room. After the induction of anesthesia, his blood pressure decreased to 47/33 mmHg. The patient's hypotension did not improve even after noradrenaline was administered. After awakening from anesthesia, the patient's systolic blood pressure increased to approximately 100 mmHg, but approximately 5 hours after returning to the ward, cardiac arrest occurred for approximately 12 seconds.<BR><B>CONCLUSIONS: </B>We experienced a case of postoperative cardiac arrest in a patient, probably owing to the use of 5-aminolevulinic acid. Although the cause of cardiac arrest is unknown, perioperative hemodynamic management must be carefully performed in patients taking 5-aminolevulinic acid.