PDF(Pubmed)
Abstract：
UNASSIGNED: Escherichia coli infection is one of the major diarrheal diseases resulting in the loss of pigs at a young age.
UNASSIGNED: This research investigated the antimicrobial activity of Caesalpinia sappan wood extract against E. coli infection as an antibiotic replacement.
UNASSIGNED: E. coli was cultured from diarrheal piglets and then used to find the minimal inhibition concentration (MIC). Caesalpinia sappan wood extract (500 mg/kg) was used for the treatment of diarrheal piglets compared to antibiotics (enrofloxacin 5 mg/kg) by oral administration. Another three groups of diarrheal piglets were used supplemented feed with 1% and 2% extract compared with commercial feed. Subsequently, E. coli enumeration, fecal shape, fecal color, and growth rate were recorded from day 1 to 7.
UNASSIGNED: Based on the results, C. sappan wood extract could inhibit E. coli growth at a MIC of 16-34 mg/ml. The number of colonies did not significantly differ between C. sappan wood extract and enrofloxacin treatment groups. A supplemented feed with 1% and 2% C. sappan wood extract could improve the fecal shape and fecal score compared to the control group, albeit only in suckling pigs. There were significant differences from the control group on days 4, 5, 6, and 7 (p < 0.05). However, the average daily gain did not significantly differ among the three groups.
UNASSIGNED: The results indicate that C. sappan wood extract could improve diarrheal signs in suckling pigs and can be used as a replacement for antibiotics for organic pig production.
UNASSIGNED: This research investigated the antimicrobial activity of Caesalpinia sappan wood extract against E. coli infection as an antibiotic replacement.
UNASSIGNED: E. coli was cultured from diarrheal piglets and then used to find the minimal inhibition concentration (MIC). Caesalpinia sappan wood extract (500 mg/kg) was used for the treatment of diarrheal piglets compared to antibiotics (enrofloxacin 5 mg/kg) by oral administration. Another three groups of diarrheal piglets were used supplemented feed with 1% and 2% extract compared with commercial feed. Subsequently, E. coli enumeration, fecal shape, fecal color, and growth rate were recorded from day 1 to 7.
UNASSIGNED: Based on the results, C. sappan wood extract could inhibit E. coli growth at a MIC of 16-34 mg/ml. The number of colonies did not significantly differ between C. sappan wood extract and enrofloxacin treatment groups. A supplemented feed with 1% and 2% C. sappan wood extract could improve the fecal shape and fecal score compared to the control group, albeit only in suckling pigs. There were significant differences from the control group on days 4, 5, 6, and 7 (p < 0.05). However, the average daily gain did not significantly differ among the three groups.
UNASSIGNED: The results indicate that C. sappan wood extract could improve diarrheal signs in suckling pigs and can be used as a replacement for antibiotics for organic pig production.
摘要：
■大肠杆菌感染是导致幼年猪损失的主要腹泻疾病之一。
■本研究调查了作为抗生素替代品的凯撒木提取物对大肠杆菌感染的抗菌活性。
■E.从腹泻仔猪中培养大肠杆菌，然后用于找到最小抑制浓度（MIC）。与抗生素（恩诺沙星5mg/kg）相比，通过口服给药，使用Caesalpiniasappan木提取物（500mg/kg）治疗腹泻仔猪。与商业饲料相比，另外三组腹泻仔猪使用补充有1％和2％提取物的饲料。随后，大肠杆菌计数，粪便形状，粪便颜色,从第1天到第7天记录生长速率。
■根据结果，苏木提取物在16-34mg/ml的MIC下可以抑制大肠杆菌生长。C.sappan木提取物和恩诺沙星处理组之间的菌落数没有显着差异。与对照组相比，添加1％和2％C.sappan木提取物的饲料可以改善粪便形状和粪便评分，虽然只有乳猪。在第4、5、6和7天与对照组存在显著差异(p<0.05)。然而,三组间的平均日增重无显著差异.
■结果表明，C.sappan木材提取物可以改善乳猪的腹泻症状，并且可以用作有机猪生产中抗生素的替代品。
■本研究调查了作为抗生素替代品的凯撒木提取物对大肠杆菌感染的抗菌活性。
■E.从腹泻仔猪中培养大肠杆菌，然后用于找到最小抑制浓度（MIC）。与抗生素（恩诺沙星5mg/kg）相比，通过口服给药，使用Caesalpiniasappan木提取物（500mg/kg）治疗腹泻仔猪。与商业饲料相比，另外三组腹泻仔猪使用补充有1％和2％提取物的饲料。随后，大肠杆菌计数，粪便形状，粪便颜色,从第1天到第7天记录生长速率。
■根据结果，苏木提取物在16-34mg/ml的MIC下可以抑制大肠杆菌生长。C.sappan木提取物和恩诺沙星处理组之间的菌落数没有显着差异。与对照组相比，添加1％和2％C.sappan木提取物的饲料可以改善粪便形状和粪便评分，虽然只有乳猪。在第4、5、6和7天与对照组存在显著差异(p<0.05)。然而,三组间的平均日增重无显著差异.
■结果表明，C.sappan木材提取物可以改善乳猪的腹泻症状，并且可以用作有机猪生产中抗生素的替代品。
