PDF(Pubmed)
Abstract：
BACKGROUND: Prevalence of youth nicotine vaping has increased, heightening concerns around negative health effects. This study aimed to compare self-reported respiratory symptoms among youth by vaping behaviours.
METHODS: Participants (n = 39,214) aged 16-19 from the 2020 and 2021 International Tobacco Control Policy Evaluation Project (ITC) Youth Tobacco and Vaping Surveys (Canada, England, US). Weighted multivariable logistic regression assessed associations between reporting any of five respiratory symptoms in the past week (shortness of breath, wheezing, chest pain, phlegm, cough) and: past 30-day smoking and/or vaping; lifetime/current vaping. Among past-30-day vapers (n = 4644), we assessed associations between symptoms and vaping frequency, use of nicotine salts, usual flavour and device type(s).
RESULTS: Overall, 27.8% reported experiencing any of the five respiratory symptoms. Compared with youth who had only vaped, those who had only smoked had similar odds of symptoms [adjusted odds ratio, OR (95% confidence interval, CI): 0.97 (0.85-1.10)], those who both smoked and vaped had higher odds [1.26 (1.12-1.42)], and those who had done neither, lower odds [0.67 (0.61-0.72)]. Compared with those who had never vaped, past use, experimentation and current regular or occasional use were all associated with higher odds. Reporting usually using nicotine salts was associated with higher odds of symptoms [1.43 (1.22-1.68)] than non-salt but was often uncertain. Compared with tobacco flavour (including with menthol), menthol/mint and sweets flavours were associated with similar odds; fruit [1.44 (1.07-1.93)], multiple [1.76 (1.30-2.39)] and \'other\' [2.14 (1.45-3.16)] flavours with higher odds. All device types were associated with similar odds.
CONCLUSIONS: Among youth, vaping was associated with increased reporting of past-week respiratory symptoms. Among those who vaped, some flavour types and potentially nicotine salts were associated with respiratory symptoms.
METHODS: Participants (n = 39,214) aged 16-19 from the 2020 and 2021 International Tobacco Control Policy Evaluation Project (ITC) Youth Tobacco and Vaping Surveys (Canada, England, US). Weighted multivariable logistic regression assessed associations between reporting any of five respiratory symptoms in the past week (shortness of breath, wheezing, chest pain, phlegm, cough) and: past 30-day smoking and/or vaping; lifetime/current vaping. Among past-30-day vapers (n = 4644), we assessed associations between symptoms and vaping frequency, use of nicotine salts, usual flavour and device type(s).
RESULTS: Overall, 27.8% reported experiencing any of the five respiratory symptoms. Compared with youth who had only vaped, those who had only smoked had similar odds of symptoms [adjusted odds ratio, OR (95% confidence interval, CI): 0.97 (0.85-1.10)], those who both smoked and vaped had higher odds [1.26 (1.12-1.42)], and those who had done neither, lower odds [0.67 (0.61-0.72)]. Compared with those who had never vaped, past use, experimentation and current regular or occasional use were all associated with higher odds. Reporting usually using nicotine salts was associated with higher odds of symptoms [1.43 (1.22-1.68)] than non-salt but was often uncertain. Compared with tobacco flavour (including with menthol), menthol/mint and sweets flavours were associated with similar odds; fruit [1.44 (1.07-1.93)], multiple [1.76 (1.30-2.39)] and \'other\' [2.14 (1.45-3.16)] flavours with higher odds. All device types were associated with similar odds.
CONCLUSIONS: Among youth, vaping was associated with increased reporting of past-week respiratory symptoms. Among those who vaped, some flavour types and potentially nicotine salts were associated with respiratory symptoms.
摘要：
背景：青少年尼古丁吸烟的患病率有所增加，增加对健康负面影响的担忧。这项研究旨在通过电子烟行为比较年轻人自我报告的呼吸道症状。
方法：2020年和2021年国际烟草控制政策评估项目（ITC）青年烟草和Vaping调查的16-19岁参与者（n=39,214）（加拿大，英格兰,美国)。加权多变量逻辑回归评估了过去一周报告的五种呼吸道症状中的任何一种之间的关联（呼吸急促，喘息,胸痛,痰,咳嗽)和：过去30天吸烟和/或电子烟；终生/当前电子烟。在过去30天的vapers中（n=4644），我们评估了症状和电子烟频率之间的关联，使用尼古丁盐，通常的味道和设备类型。
结果：总体而言，27.8％的人报告经历了五种呼吸道症状中的任何一种。与只吸过烟的年轻人相比，那些只吸烟的人有相似的症状几率[调整后的优势比，或(95%置信区间，CI）：0.97（0.85-1.10）]，吸烟和吸食的人的赔率较高[1.26（1.12-1.42）]，那些没有做过的人，较低的赔率[0.67（0.61-0.72）]。与那些从未吸过烟的人相比，过去的使用，实验和目前定期或偶尔使用都与较高的几率相关.通常使用尼古丁盐的报告与非盐相比，症状的几率更高[1.43（1.22-1.68）]，但通常不确定。与烟草香料（包括薄荷醇）相比，薄荷醇/薄荷和甜食口味与相似的几率相关；水果[1.44(1.07-1.93)]，多种[1.76（1.30-2.39）]和\'其他\'[2.14（1.45-3.16）]风味，赔率较高。所有设备类型都与相似的赔率相关。
结论：在年轻人中，vaping与过去一周呼吸道症状报告增加相关.在那些吸电子烟的人中，一些香精类型和潜在的尼古丁盐与呼吸道症状有关.
方法：2020年和2021年国际烟草控制政策评估项目（ITC）青年烟草和Vaping调查的16-19岁参与者（n=39,214）（加拿大，英格兰,美国)。加权多变量逻辑回归评估了过去一周报告的五种呼吸道症状中的任何一种之间的关联（呼吸急促，喘息,胸痛,痰,咳嗽)和：过去30天吸烟和/或电子烟；终生/当前电子烟。在过去30天的vapers中（n=4644），我们评估了症状和电子烟频率之间的关联，使用尼古丁盐，通常的味道和设备类型。
结果：总体而言，27.8％的人报告经历了五种呼吸道症状中的任何一种。与只吸过烟的年轻人相比，那些只吸烟的人有相似的症状几率[调整后的优势比，或(95%置信区间，CI）：0.97（0.85-1.10）]，吸烟和吸食的人的赔率较高[1.26（1.12-1.42）]，那些没有做过的人，较低的赔率[0.67（0.61-0.72）]。与那些从未吸过烟的人相比，过去的使用，实验和目前定期或偶尔使用都与较高的几率相关.通常使用尼古丁盐的报告与非盐相比，症状的几率更高[1.43（1.22-1.68）]，但通常不确定。与烟草香料（包括薄荷醇）相比，薄荷醇/薄荷和甜食口味与相似的几率相关；水果[1.44(1.07-1.93)]，多种[1.76（1.30-2.39）]和\'其他\'[2.14（1.45-3.16）]风味，赔率较高。所有设备类型都与相似的赔率相关。
结论：在年轻人中，vaping与过去一周呼吸道症状报告增加相关.在那些吸电子烟的人中，一些香精类型和潜在的尼古丁盐与呼吸道症状有关.
