PDF(Pubmed)
Abstract：
Repair and reconstruction of the myopectineal orifice area using meshes is the mainstay of surgical treatment of inguinal hernias. However, the limitations of existing meshes are becoming increasingly evident in clinical applications; thus, the idea of using three-dimensionally (3D)-printed biological meshes was put forward. According to the current level of the 3D printing technology and the inherent characteristics of biological materials, the direct use of the 3D printing technology for making biological materials into finished products suitable for clinical applications is not yet supported, but synthetic materials can be first printed into 3D form carriers, compounded with biological materials, and finally made into finished products. The purpose of this study was to develop a technical protocol for making 3D-printed biomesh carriers using polyurethane as a raw material. In our study: raw material, polyurethane; weight, 20-30 g/m2; weaving method, hexagonal mesh; elastic tension aspect ratio, 2:1; diameters of pores, 0.1-1 mm; surface area, 8 × 12 cm2; the optimal printing layer height, temperature and velocity were 0.1 mm, 210-220 °C and 60 mm/s. Its clinical significance lies in: (1) applied to preoperative planning and design a detailed surgical plan; (2) applied to special types of surgery including patients in puberty, recurrent and compound inguinal hernias; (3) significantly improve the efficiency of doctor-patient communication; (4) it can shorten the operation and recovery period by about 1/3 and can save about 1/4 of the cost for patients; (5) the learning curve is significantly shortened, which is conducive to the cultivation of reserve talents.
摘要：
使用网状物修复和重建肌开放孔区是腹股沟疝手术治疗的主要手段。然而,现有网格的局限性在临床应用中越来越明显；因此，提出了使用三维（3D）打印生物网格的想法。根据目前的3D打印技术水平和生物材料的固有特性,尚不支持直接使用3D打印技术将生物材料制成适合临床应用的成品，但是合成材料可以首先打印成3D形式的载体，与生物材料复合，最后制成成品。这项研究的目的是开发一种使用聚氨酯作为原料制造3D打印生物网格载体的技术方案。在我们的研究中：原材料，聚氨酯;重量,20-30g/m2；编织方法，六边形网格;弹性张力长宽比,2:1;孔径,0.1-1毫米；表面积，8×12cm2；最佳印刷层高度，温度和速度为0.1毫米，210-220°C和60mm/s。其临床意义在于:(1)适用于术前规划和设计详细的手术方案;(2)适用于特殊类型的手术,复发性和复合性腹股沟疝；（3）显著提高医患沟通效率；（4）可缩短手术和恢复期约1/3，可为患者节省约1/4的费用；（5）学习曲线显著缩短，有利于后备人才的培养。
