Abstract：
OBJECTIVE: To define the regular upper eyelid anatomy and their changes during dynamic motion using ultrasonographically depicted structures.
METHODS: A cross-sectional study.
METHODS: High-resolution ultrasound biomicroscopy (50MHz) was performed on 84 upper eyelids of 42 healthy volunteers without evidence of eyelid conditions. The skin-orbicularis oculi complex (SOOC), levator aponeurosis, and Müller\'s muscle-conjunctival complex were imaged. The thickness of these structures was measured in primary gaze and downgaze positions.
RESULTS: SOOC and levator aponeurosis thickness was bigger with eyes open than with eyes closed (p < 0.01). With eyes closed, the thickness of SOOC on the pupillary midline and levator aponeurosis was positively correlated with age (p < 0.05, p < 0.01, respectively), and the thickness of levator aponeurosis and SOOC on the pupil midline was also positively correlated with BMI index (p < 0.05). Similarly, SOOC thickness on the medial and lateral canthus line is also positively correlated with BMI index and age (p < 0.05, p < 0.01, respectively). As for the differences between genders, the mean thickness of SOOC and levator aponeurosis was statistically different (p < 0.05, respectively). The magnitude of levator aponeurosis thickness in men varied more than in women in different ocular positions (p < 0.05). All measurements had an intramethod between 0.624 and 0.792, and inter-rater ICC and intrarater ICC between 0.748 and 0.850.
CONCLUSIONS: Ultrasound biomicroscopy represents a noninvasive tool for the visualization of upper eyelid morphology. Expanding its application can help to understand the dynamics of upper eyelid physiological movement, aging, and disease research in different populations and evaluate surgical outcomes.
METHODS: A cross-sectional study.
METHODS: High-resolution ultrasound biomicroscopy (50MHz) was performed on 84 upper eyelids of 42 healthy volunteers without evidence of eyelid conditions. The skin-orbicularis oculi complex (SOOC), levator aponeurosis, and Müller\'s muscle-conjunctival complex were imaged. The thickness of these structures was measured in primary gaze and downgaze positions.
RESULTS: SOOC and levator aponeurosis thickness was bigger with eyes open than with eyes closed (p < 0.01). With eyes closed, the thickness of SOOC on the pupillary midline and levator aponeurosis was positively correlated with age (p < 0.05, p < 0.01, respectively), and the thickness of levator aponeurosis and SOOC on the pupil midline was also positively correlated with BMI index (p < 0.05). Similarly, SOOC thickness on the medial and lateral canthus line is also positively correlated with BMI index and age (p < 0.05, p < 0.01, respectively). As for the differences between genders, the mean thickness of SOOC and levator aponeurosis was statistically different (p < 0.05, respectively). The magnitude of levator aponeurosis thickness in men varied more than in women in different ocular positions (p < 0.05). All measurements had an intramethod between 0.624 and 0.792, and inter-rater ICC and intrarater ICC between 0.748 and 0.850.
CONCLUSIONS: Ultrasound biomicroscopy represents a noninvasive tool for the visualization of upper eyelid morphology. Expanding its application can help to understand the dynamics of upper eyelid physiological movement, aging, and disease research in different populations and evaluate surgical outcomes.
摘要：
目的：使用超声描绘的结构来定义上眼睑的规则解剖结构及其在动态运动过程中的变化。
方法：横断面研究。
方法：对42名健康志愿者的84个上眼睑进行了高分辨率超声生物显微镜检查（50MHz），没有眼睑状况的证据。皮肤-眼轮匝复合体（SOOC），提肌肌腱膜,和Müller的肌肉结膜复合体成像。在主要凝视和向下凝视位置测量这些结构的厚度。
结果：睁眼时SOOC和提膜膜厚度大于闭眼时（p<0.01）。闭着眼睛,瞳孔中线和提上膜膜的SOOC厚度与年龄呈正相关（分别为p<0.05，p<0.01），瞳孔中线提上肌腱膜和SOOC的厚度与BMI指数也呈正相关（p<0.05）。同样，内侧和外侧can线的SOOC厚度也与BMI指数和年龄呈正相关（分别为p<0.05，p<0.01）。至于性别之间的差异，SOOC和提上膜膜的平均厚度有统计学差异（分别为p<0.05）。在不同的眼位，男性的提上肌腱膜厚度的变化幅度大于女性的差异（p<0.05）。所有测量值的内法在0.624和0.792之间，评估者之间的ICC和内部ICC在0.748和0.850之间。
结论：超声生物显微镜检查是一种非侵入性的上眼睑形态可视化工具。扩展其应用可以帮助了解上睑生理运动的动力学，老化，和不同人群的疾病研究，并评估手术结果。
方法：横断面研究。
方法：对42名健康志愿者的84个上眼睑进行了高分辨率超声生物显微镜检查（50MHz），没有眼睑状况的证据。皮肤-眼轮匝复合体（SOOC），提肌肌腱膜,和Müller的肌肉结膜复合体成像。在主要凝视和向下凝视位置测量这些结构的厚度。
结果：睁眼时SOOC和提膜膜厚度大于闭眼时（p<0.01）。闭着眼睛,瞳孔中线和提上膜膜的SOOC厚度与年龄呈正相关（分别为p<0.05，p<0.01），瞳孔中线提上肌腱膜和SOOC的厚度与BMI指数也呈正相关（p<0.05）。同样，内侧和外侧can线的SOOC厚度也与BMI指数和年龄呈正相关（分别为p<0.05，p<0.01）。至于性别之间的差异，SOOC和提上膜膜的平均厚度有统计学差异（分别为p<0.05）。在不同的眼位，男性的提上肌腱膜厚度的变化幅度大于女性的差异（p<0.05）。所有测量值的内法在0.624和0.792之间，评估者之间的ICC和内部ICC在0.748和0.850之间。
结论：超声生物显微镜检查是一种非侵入性的上眼睑形态可视化工具。扩展其应用可以帮助了解上睑生理运动的动力学，老化，和不同人群的疾病研究，并评估手术结果。
