Abstract：
OBJECTIVE: This review aimed to address the limited evidence on the efficacy of continuation or maintenance electroconvulsive therapy (C/M-ECT) in schizophrenia, with a focus on international case reports and series due to the scarcity of randomised controlled trials.
METHODS: Electronic database searches were conducted to identify case reports or series evaluating the efficacy of C/M-ECT in patients with schizophrenia or schizoaffective disorder.
RESULTS: C/M-ECT treatment span varied from 3 months to 36 years (Median = 30 months; M = 43.9 months; SD = 63.0) and was effective in maintaining remission for most patients with schizophrenia in combination with antipsychotic medication. Reporting of adverse events including cognitive adverse effects was infrequent.
CONCLUSIONS: Collation of case reports and series data indicated that C/M-ECT, when combined with antipsychotics, appears to be a safe and effective strategy for maintaining remission, even over several years. Caution is warranted due to the potential influence of publication bias.
METHODS: Electronic database searches were conducted to identify case reports or series evaluating the efficacy of C/M-ECT in patients with schizophrenia or schizoaffective disorder.
RESULTS: C/M-ECT treatment span varied from 3 months to 36 years (Median = 30 months; M = 43.9 months; SD = 63.0) and was effective in maintaining remission for most patients with schizophrenia in combination with antipsychotic medication. Reporting of adverse events including cognitive adverse effects was infrequent.
CONCLUSIONS: Collation of case reports and series data indicated that C/M-ECT, when combined with antipsychotics, appears to be a safe and effective strategy for maintaining remission, even over several years. Caution is warranted due to the potential influence of publication bias.
摘要：
目的：这篇综述旨在解决精神分裂症持续或维持电惊厥治疗（C/M-ECT）疗效的有限证据，由于随机对照试验的稀缺性，重点关注国际病例报告和系列。
方法：进行电子数据库搜索，以确定病例报告或系列评估C/M-ECT在精神分裂症或分裂情感障碍患者中的疗效。
结果：C/M-ECT治疗时间从3个月到36年不等（中位数=30个月；M=43.9个月；SD=63.0），对于大多数精神分裂症患者联合抗精神病药物治疗可有效维持缓解。包括认知不良反应在内的不良事件的报告并不常见。
结论：病例报告和系列数据的整理表明，C/M-ECT，当与抗精神病药物合用时，似乎是维持缓解的安全有效的策略，甚至超过几年。由于出版偏见的潜在影响，谨慎是必要的。
方法：进行电子数据库搜索，以确定病例报告或系列评估C/M-ECT在精神分裂症或分裂情感障碍患者中的疗效。
结果：C/M-ECT治疗时间从3个月到36年不等（中位数=30个月；M=43.9个月；SD=63.0），对于大多数精神分裂症患者联合抗精神病药物治疗可有效维持缓解。包括认知不良反应在内的不良事件的报告并不常见。
结论：病例报告和系列数据的整理表明，C/M-ECT，当与抗精神病药物合用时，似乎是维持缓解的安全有效的策略，甚至超过几年。由于出版偏见的潜在影响，谨慎是必要的。
