PDF(Pubmed)
Abstract：
UNASSIGNED: We evaluated the characteristics of carotid and vertebral atherosclerosis in indigenous West Africans with stroke.
UNASSIGNED: Of the 3778stroke patients recruited between 01/2014 and 08/2017, 1070 (28.3%) received carotid and vertebral artery evaluation with B-mode Ultrasound. Carotid and vertebral intima-media thickness (IMT) using multiple site technique were measured bilaterally and plaque frequency was determined. Descriptive and comparative analyses between stroke types and vessels were carried out.
UNASSIGNED: There were 809 (75.6%) patients with ischemic stroke. The prevalence of intima-media thickening in the study population was 84.0% (898/1070) [95% CI: 81.7-86.1], being higher in the ischemic stroke (688/809, 85.0%) [95% CI: 82.4-87.3] than in the hemorrhagic stroke group (211/261, 80.8%) [95% CI: 75.6-85.2]. Overall prevalence of plaques which was 26.1% [95% CI: 23.5-28.8], was found also to be higher in ischemic than hemorrhagic stroke (29.8%[95% CI: 26.7-33.0] vs. 14.6% [95% CI: 10.8-19.4], p < 0.05). The mean IMT (carotids: 2.01+1.33 mm; vertebrals: 0.96+0.54mm, p<0.001) and prevalence of plaques (carotids: 8.8%; vertebrals: 1.7%,p<0.001) were higher in carotid than vertebral arteries. Age, hypertension, level of formal education, history of smoking, average monthly income, and family histories of hypertension and stroke were associated with intima-media thickening in the carotids (all p< 0.05) in the ischemic stroke patients while family history of hypertension, diabetes mellitus, and level of formal education were independently associated with intima-media thickening in the carotids (all p< 0.05) in the hemorrhagic stroke patients. No CVRF showed an independent association with the presence of plaque in the carotid and vertebral arteries both stroke types.
UNASSIGNED: One off our stroke patients in our cohort had atherosclerotic plaques, with ischemic patients being twice as likely to have this burden compared to hemorrhagic patients, and carotid atherosclerosis being five times as frequent as vertebral atherosclerosis.
UNASSIGNED: Of the 3778stroke patients recruited between 01/2014 and 08/2017, 1070 (28.3%) received carotid and vertebral artery evaluation with B-mode Ultrasound. Carotid and vertebral intima-media thickness (IMT) using multiple site technique were measured bilaterally and plaque frequency was determined. Descriptive and comparative analyses between stroke types and vessels were carried out.
UNASSIGNED: There were 809 (75.6%) patients with ischemic stroke. The prevalence of intima-media thickening in the study population was 84.0% (898/1070) [95% CI: 81.7-86.1], being higher in the ischemic stroke (688/809, 85.0%) [95% CI: 82.4-87.3] than in the hemorrhagic stroke group (211/261, 80.8%) [95% CI: 75.6-85.2]. Overall prevalence of plaques which was 26.1% [95% CI: 23.5-28.8], was found also to be higher in ischemic than hemorrhagic stroke (29.8%[95% CI: 26.7-33.0] vs. 14.6% [95% CI: 10.8-19.4], p < 0.05). The mean IMT (carotids: 2.01+1.33 mm; vertebrals: 0.96+0.54mm, p<0.001) and prevalence of plaques (carotids: 8.8%; vertebrals: 1.7%,p<0.001) were higher in carotid than vertebral arteries. Age, hypertension, level of formal education, history of smoking, average monthly income, and family histories of hypertension and stroke were associated with intima-media thickening in the carotids (all p< 0.05) in the ischemic stroke patients while family history of hypertension, diabetes mellitus, and level of formal education were independently associated with intima-media thickening in the carotids (all p< 0.05) in the hemorrhagic stroke patients. No CVRF showed an independent association with the presence of plaque in the carotid and vertebral arteries both stroke types.
UNASSIGNED: One off our stroke patients in our cohort had atherosclerotic plaques, with ischemic patients being twice as likely to have this burden compared to hemorrhagic patients, and carotid atherosclerosis being five times as frequent as vertebral atherosclerosis.
摘要：
■我们评估了患有中风的西非土著人群的颈动脉和椎动脉粥样硬化的特征。
■在2014年01月至2017年08月招募的3778例中风患者中，有1070例（28.3％）接受了B型超声对颈动脉和椎动脉的评估。使用多部位技术测量双侧颈动脉和椎体内中膜厚度（IMT），并确定斑块频率。进行了中风类型和血管之间的描述性和比较分析。
■有809例（75.6%）缺血性卒中患者。研究人群中内膜-中膜增厚的患病率为84.0%(898/1070)[95%CI:81.7-86.1],缺血性卒中(688/809,85.0%)[95%CI:82.4-87.3]高于出血性卒中组(211/261,80.8%)[95%CI:75.6-85.2]。斑块的总体患病率为26.1％[95％CI：23.5-28.8]，在缺血性中风中也发现高于出血性中风（29.8％[95％CI：26.7-33.0]vs.14.6%[95%CI：10.8-19.4]，p<0.05)。平均IMT（颈动脉：2.01+1.33毫米；椎骨：0.96+0.54毫米，p<0.001）和斑块的患病率（颈动脉：8.8％；椎骨：1.7％，p<0.001）在颈动脉中高于椎动脉。年龄,高血压,正规教育水平，吸烟史,月平均收入,高血压和卒中家族史与缺血性卒中患者颈动脉内中膜增厚相关(均P<0.05),而高血压家族史,糖尿病,和正规教育水平与出血性卒中患者颈动脉内中膜增厚独立相关(均p<0.05)。CVRF均未显示与两种卒中类型的颈动脉和椎动脉中斑块的存在独立关联。
■我们队列中的一位中风患者有动脉粥样硬化斑块，与出血性患者相比，缺血性患者有这种负担的可能性是后者的两倍，颈动脉粥样硬化是椎骨动脉粥样硬化的五倍。
■在2014年01月至2017年08月招募的3778例中风患者中，有1070例（28.3％）接受了B型超声对颈动脉和椎动脉的评估。使用多部位技术测量双侧颈动脉和椎体内中膜厚度（IMT），并确定斑块频率。进行了中风类型和血管之间的描述性和比较分析。
■有809例（75.6%）缺血性卒中患者。研究人群中内膜-中膜增厚的患病率为84.0%(898/1070)[95%CI:81.7-86.1],缺血性卒中(688/809,85.0%)[95%CI:82.4-87.3]高于出血性卒中组(211/261,80.8%)[95%CI:75.6-85.2]。斑块的总体患病率为26.1％[95％CI：23.5-28.8]，在缺血性中风中也发现高于出血性中风（29.8％[95％CI：26.7-33.0]vs.14.6%[95%CI：10.8-19.4]，p<0.05)。平均IMT（颈动脉：2.01+1.33毫米；椎骨：0.96+0.54毫米，p<0.001）和斑块的患病率（颈动脉：8.8％；椎骨：1.7％，p<0.001）在颈动脉中高于椎动脉。年龄,高血压,正规教育水平，吸烟史,月平均收入,高血压和卒中家族史与缺血性卒中患者颈动脉内中膜增厚相关(均P<0.05),而高血压家族史,糖尿病,和正规教育水平与出血性卒中患者颈动脉内中膜增厚独立相关(均p<0.05)。CVRF均未显示与两种卒中类型的颈动脉和椎动脉中斑块的存在独立关联。
■我们队列中的一位中风患者有动脉粥样硬化斑块，与出血性患者相比，缺血性患者有这种负担的可能性是后者的两倍，颈动脉粥样硬化是椎骨动脉粥样硬化的五倍。
