PDF(Pubmed)
Abstract：
The vasa vasorum of the large pulmonary vessels is involved in the pathology of COVID-19. This specialized microvasculature plays a major role in the biology and pathology of the pulmonary vessel walls. We have evidence that thrombosis of the vasa vasorum of the large and medium-sized pulmonary vessels during severe COVID-19 causes ischemia and subsequent death of the pulmonary vasculature endothelium. Subsequent release of thrombi from the vasa interna into the pulmonary circulation and pulmonary embolism generated at the ischemic pulmonary vascular endothelium site, are the central pathophysiological mechanisms in COVID-19 responsible for pulmonary thromboembolism. The thrombosis of the vasa vasorum of the large and medium-sized pulmonary vessels is an internal event leading to pulmonary thromboembolism in COVID-19.
摘要：
大肺血管的血管血管与COVID-19的病理有关。这种特殊的微血管在肺血管壁的生物学和病理学中起着重要作用。我们有证据表明，在严重的COVID-19期间，大中型肺血管的血管血管血栓形成会导致肺血管内皮缺血和随后的死亡。随后从血管内部释放血栓进入肺循环，并在缺血性肺血管内皮部位产生肺栓塞，是COVID-19导致肺血栓栓塞的主要病理生理机制。大中型肺血管的血管血栓形成是导致COVID-19肺血栓栓塞的内部事件。
