HIF2 α 依赖性 Dock4 / Rac1 信号传导调节常氧下粘附连接的形成和细胞极性。
关键词: Adherens junction Cancer HIF Hypoxia Kidney epithelial polarity
Mesh : Adherens Junctions / metabolism Signal Transduction Cell Polarity Animals Basic Helix-Loop-Helix Transcription Factors / metabolism genetics rac1 GTP-Binding Protein / metabolism GTPase-Activating Proteins / metabolism genetics Cadherins / metabolism genetics Mice Humans Epithelial Cells / metabolism p21-Activated Kinases / metabolism genetics Cell Line
来 源:
DOI:10.1038/s41598-024-62955-7
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