关键词: Bioactive compounds Cidofovir Mechanism of action Phytochemicals Poxviruses

Mesh : Antiviral Agents / pharmacology therapeutic use Humans Poxviridae / drug effects physiology genetics Animals Poxviridae Infections / drug therapy virology Phytochemicals / therapeutic use pharmacology chemistry

来  源:   DOI:10.1007/978-3-031-57165-7_21

Abstract:
Poxviruses belong to the family of double-stranded DNA viruses, and it is pathogenic for humans and spread worldwide. These viruses cause infections and various diseases in human. So, it is required to develop new drugs for the treatment of smallpox or other poxvirus infections. Very few potential compounds for the treatment of poxvirus such as smallpox, chickenpox, and monkeypox have been reported. Most of the compounds has used as vaccines. Cidofovir is most commonly used as a vaccine for the treatment of poxviruses. There are no phytochemicals reported for the treatment of poxviruses. Very few phytochemicals are under investigation for the treatment of poxviruses.
摘要:
痘病毒属于双链DNA病毒家族,它对人类有致病性,并在世界范围内传播。这些病毒在人类中引起感染和各种疾病。所以,需要开发治疗天花或其他痘病毒感染的新药。治疗痘病毒如天花的潜在化合物很少,水痘,和猴痘都有报道。大多数化合物已用作疫苗。西多福韦是最常用的疫苗用于治疗痘病毒。没有报道用于治疗痘病毒的植物化学物质。很少有植物化学物质正在研究用于治疗痘病毒。
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