Mesh : Humans Female Adult Urinary Tract Infections / diagnosis microbiology urine Sexually Transmitted Diseases / urine diagnosis microbiology Gonorrhea / diagnosis urine Urinalysis / methods Chlamydia Infections / urine diagnosis Middle Aged Chlamydia trachomatis / isolation & purification Emergency Service, Hospital Trichomonas vaginalis / isolation & purification Bacteriuria / diagnosis urine microbiology Young Adult Neisseria gonorrhoeae / isolation & purification Urine / microbiology Retrospective Studies Adolescent Trichomonas Infections / diagnosis urine

来  源:   DOI:10.5811/westjem.60033   PDF(Pubmed)

Abstract:
UNASSIGNED: Bacterial urinary tract infections (UTI) and some sexually transmitted infections (STI) can have overlapping signs and symptoms or nonspecific findings, such as pyuria on urinalysis. Furthermore, results from the urine culture and the nucleic acid amplification test for an STI may not be available during the clinical encounter. We sought to determine whether gonorrhea, chlamydia, and trichomoniasis are associated with bacteriuria, information that might aid in the differentiation of STIs and UTIs.
UNASSIGNED: We used multinomial logistic regression to analyze 9,650 encounters of female patients who were aged ≥18 years and who underwent testing for STIs. The ED encounters took place from April 18, 2014-March 7, 2017. We used a multivariable regression analysis to account for patient demographics, urinalysis findings, vaginal wet-mount results, and positive or negative (or no) findings from the urine culture and testing for Neisseria gonorrhoeae, Chlamydia trachomatis, or Trichomonas vaginalis.
UNASSIGNED: In multivariable analysis, infection with T vaginalis, N gonorrhoeae, or C trachomatis was not associated with having a urine culture yielding 10,000 or more colony-forming units per mililiter (CFU/mL) of bacteria compared with a urine culture yielding less than 10,000 CFU/mL or no urine culture obtained. The diagnosis of a UTI in the ED was not associated with having a urine culture yielding 10,000 or more CFU/mL compared with a urine culture yielding less than 10,000 CFU/mL.
UNASSIGNED: After adjusting for covariates, no association was observed between urine culture results and testing positive for trichomoniasis, gonorrhea, or chlamydia. Our results suggest that having a concurrent STI and bacterial UTI is unlikely.
摘要:
细菌性尿路感染(UTI)和某些性传播感染(STI)可能有重叠的体征和症状或非特异性发现,如尿液分析中的脓尿。此外,在临床治疗期间,尿液培养和STI核酸扩增试验的结果可能无法获得.我们试图确定淋病,衣原体,滴虫病与菌尿有关,可能有助于性传播感染和尿路感染区分的信息。
我们使用多项逻辑回归分析了9650例年龄≥18岁并接受性传播感染检测的女性患者。ED相遇发生在2014年4月18日至2017年3月7日。我们使用多变量回归分析来解释患者的人口统计学,尿液分析结果,阴道湿装结果,尿液培养和淋病奈瑟菌检测结果呈阳性或阴性(或无),沙眼衣原体,或者阴道毛滴虫.
在多变量分析中,阴道T细胞感染,淋病N,或沙眼衣原体与尿培养物产生10,000或更多菌落形成单位/毫升(CFU/mL)细菌的尿培养物无关,而尿培养物产生少于10,000CFU/mL或未获得尿培养物。ED中UTI的诊断与尿培养物产生10,000或更高的CFU/mL无关,而尿培养物产生少于10,000CFU/mL。
调整协变量后,尿培养结果与滴虫检测阳性之间未观察到关联,淋病,或者衣原体.我们的结果表明,并发STI和细菌UTI不太可能。
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