关键词: Epimedium Linn. clinical application pharmacological phytochemistry quality control

Mesh : Epimedium / chemistry Humans Quality Control Drugs, Chinese Herbal / chemistry pharmacology isolation & purification Animals Medicine, Chinese Traditional Phytochemicals / pharmacology chemistry isolation & purification

来  源:   DOI:10.1002/cbdv.202400846

Abstract:
Epimedium genus is a traditional Chinese medicine, which has functions of tonifying kidney and yang, strengthening tendons and bones, dispelling wind and emoving dampness. It is mainly used for the treatment of impotence and spermatorrhea, osteoporosis, Parkinson\'s, Alzheimer\'s, and cardiovascular diseases. The aim of this review is to provide a systematic summary of the phytochemistry, pharmacology, and clinical applications of the Epimedium Linn. In this paper, the relevant literature on Epimedium Linn. was collected from 1987 to the present day, and more than 274 chemical constituents, including flavonoids, phenylpropanoids, lignans, phenanthrenes, and others, were isolated from this genus. Modern pharmacological studies have shown that Epimedium Linn. has osteoprotective, neuroprotective, cardiovascular protective, and immune enhancing pharmacological effects. In addition, Epimedium Linn. has been commonly used to treat osteoporosis, erectile dysfunction, hypertension and cardiovascular disease. In this paper, the distribution of resources, chemical compositions, pharmacological effects, clinical applications and quality control of Epimedium Linn. are progressed to provide a reference for further research and development of the resources of this genus.
摘要:
淫羊藿属是一种传统的中药,具有补肾和阳气的功能,加强肌腱和骨骼,驱风除湿。它主要用于治疗阳痿和遗精,骨质疏松,帕金森,老年痴呆症,和心血管疾病。这篇综述的目的是对植物化学进行系统的总结,药理学,淫羊藿的临床应用。在本文中,淫羊藿的相关文献。是从1987年至今收集的,和超过274种化学成分,包括类黄酮,苯丙素类化合物,木脂素,菲,和其他人,是从这个属中分离出来的。现代药理研究表明淫羊藿属。具有骨保护作用,神经保护,心血管保护,和免疫增强药理作用。此外,淫羊藿.通常用于治疗骨质疏松症,勃起功能障碍,高血压和心血管疾病。在本文中,资源的分配,化学成分,药理作用,淫羊藿临床应用及质量控制.为该属资源的进一步研究和开发提供参考。
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