UNASSIGNED: Cross-sectional study.
UNASSIGNED: A total of 250 individuals (198 males and 52 females) working in mining areas were examined, and their oral findings were recorded in a proforma. For the micro-nucleus assay, buccal smears from 30 individuals working in mining areas with habits, 30 individuals working in mining areas without habits, and 30 individuals residing in non-mining areas (control group) were selected. Smears were stained with Giemsa stain to identity and quantify the MNs.
UNASSIGNED: The frequency of oral mucosal problems among 250 persons working in mining regions was 170 (68.0%) with no oral mucosal conditions, 79 (32.6%) with oral mucosal conditions, 25 (10%) with leukoplakia, 1 (0.4%) with lichen planus, and 8 (3.2%) with ulcerations. Acute necrotising gingivitis was reported in one person (0.4%), candidiasis in two (0.8%), abscess in two (0.8%), OSMF in 39 (15.6%), and oral cancer in two (0.8%). The mean MN count was 2.40 + 1.57 in mine employees with habits, 2.18 + 1.25 in mine workers without habits, and 1.40 + 0.55 in normal healthy controls.
UNASSIGNED: Reduced occupational health risks brought on by exposure to mining contaminants require protective measures. After being exposed to mining pollutants, exfoliated buccal mucosal cells can be examined for genotoxicity.
■横断面研究。
■共检查了在矿区工作的250个人(198名男性和52名女性),他们的口头发现以形式记录。对于微核测定,来自30名在矿区工作的有习惯的人的口腔涂片,30个人在矿区工作没有习惯,选择居住在非矿区的30人(对照组)。涂片用Giemsa染色剂染色以鉴定和定量MN。
■在矿区工作的250个人中,没有口腔黏膜疾病的口腔黏膜问题的频率为170(68.0%),79(32.6%)患有口腔粘膜疾病,25(10%)患有白斑,1例(0.4%)扁平苔藓,溃疡8例(3.2%)。急性坏死性牙龈炎报告1人(0.4%),念珠菌病两例(0.8%),两个脓肿(0.8%),OSMF在39(15.6%),和口腔癌两个(0.8%)。有习惯的矿山员工的平均MN计数为2.40+1.57,2.18+1.25在没有习惯的矿井工人中,正常健康对照组为1.40+0.55。
■减少接触采矿污染物带来的职业健康风险需要采取保护措施。暴露于采矿污染物后,可以检查脱落的口腔粘膜细胞的遗传毒性。