%0 Journal Article
%T The adverse effects of mining pollutants on oral mucosa in Bellary district: A clinical and genotoxicity study.
%A Bellary IR
%A Prabhu VD
%A Jose M
%A Abdulla R
%A Shetty UA
%J J Oral Maxillofac Pathol
%V 28
%N 1
%D 2024 Jan-Mar
%M 38800431
暂无%R 10.4103/jomfp.jomfp_414_23
%X <B>UNASSIGNED: </B>The Bellary district in Karnataka, rich in mineral resources, is a major mining industry, but prolonged exposure to mining can lead to health hazards. The study aims to assess the genotoxic impact of mining pollutants on mine workers using the micro-nucleus (MN) assay.<BR><B>UNASSIGNED: </B>Cross-sectional study.<BR><B>UNASSIGNED: </B>A total of 250 individuals (198 males and 52 females) working in mining areas were examined, and their oral findings were recorded in a proforma. For the micro-nucleus assay, buccal smears from 30 individuals working in mining areas with habits, 30 individuals working in mining areas without habits, and 30 individuals residing in non-mining areas (control group) were selected. Smears were stained with Giemsa stain to identity and quantify the MNs.<BR><B>UNASSIGNED: </B>The frequency of oral mucosal problems among 250 persons working in mining regions was 170 (68.0%) with no oral mucosal conditions, 79 (32.6%) with oral mucosal conditions, 25 (10%) with leukoplakia, 1 (0.4%) with lichen planus, and 8 (3.2%) with ulcerations. Acute necrotising gingivitis was reported in one person (0.4%), candidiasis in two (0.8%), abscess in two (0.8%), OSMF in 39 (15.6%), and oral cancer in two (0.8%). The mean MN count was 2.40 + 1.57 in mine employees with habits, 2.18 + 1.25 in mine workers without habits, and 1.40 + 0.55 in normal healthy controls.<BR><B>UNASSIGNED: </B>Reduced occupational health risks brought on by exposure to mining contaminants require protective measures. After being exposed to mining pollutants, exfoliated buccal mucosal cells can be examined for genotoxicity.