PDF(Pubmed)
Abstract：
Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome is a type of seronegative arthritis characterized by a favorable prognosis (Remitting), absence of rheumatoid factor (Seronegative), symmetry (Symmetrical), and synovitis with pitting edema on the backs of the hands and feet. The cause of RS3PE syndrome remains unknown, but involvement of the immune system is suspected, and steroids are highly effective. Here, we present a case of an 86-year-old woman with severe anemia and bilateral lower limb edema accompanied by chronic eczema, considered to be caused by RS3PE syndrome. The patient\'s symptoms included bilateral lower limb edema, allergic rash, cognitive decline, and difficulty in moving, all of which were attributed to RS3PE syndrome. Given the variety of systemic symptoms associated with RS3PE syndrome, which can significantly impair the activities of daily living (ADLs) in the elderly, early detection and treatment are crucial.
摘要：
缓解性血清阴性对称性滑膜炎伴凹陷性水肿（RS3PE）综合征是一种血清阴性关节炎，其特征是预后良好（缓解），没有类风湿因子（血清阴性），对称（对称），以及手脚背部有凹陷性水肿的滑膜炎。RS3PE综合征的病因尚不清楚，但是怀疑是免疫系统的参与，类固醇非常有效。这里,我们介绍了一例86岁的女性，患有严重贫血和双侧下肢水肿并伴有慢性湿疹，认为是由RS3PE综合征引起的。患者的症状包括双侧下肢水肿，过敏性皮疹,认知能力下降,移动困难，所有这些都归因于RS3PE综合征。鉴于与RS3PE综合征相关的各种全身症状，这会显著损害老年人的日常生活活动(ADLs)，早期发现和治疗至关重要。
