PDF(Pubmed)
Abstract：
UNASSIGNED: The European Working Group on Sarcopenia in Older People (EWGSOP) has put forward two key proposals for diagnosing sarcopenia: the EWGSOP1 in 2010 and the EWGSOP2 in 2019. These proposals are currently the most widely used guidelines for diagnosing sarcopenia. However, data on the prevalence of sarcopenia in patients with rheumatoid arthritis (RA) based on EWGSOP criteria are limited. This study aimed to: (a) establish the prevalence of sarcopenia in an elderly Spanish cohort of women with RA using both EWGSOP1 and EWGSOP2 criteria; and (b) evaluate the effectiveness of the SARC-F questionnaire in detecting sarcopenia.
UNASSIGNED: In this observational, cross-sectional study, 67 women aged over 65 years who met the ACR 2010 criteria for RA were consecutively recruited from a tertiary university hospital. Assessments included: (a) demographic and anthropometric data; (b) RA-related variables (disease history, analytical evaluation, activity, disability, quality of life); and (c) sarcopenia-related variables (muscle strength, gait speed, skeletal muscle mass, and SARC-F questionnaire). The prevalence of sarcopenia was determined using both EWGSOP1 and EWGSOP2 criteria. Furthermore, the effectiveness of the SARC-F questionnaire for detecting sarcopenia were calculated.
UNASSIGNED: The prevalence of sarcopenia was 43% according to the EWGSOP1 criteria and 16% according to the EWGSOP2 criteria. Patients diagnosed with sarcopenia based on the latter criteria also met the EWGSOP1\'s criteria for sarcopenia. Agreement between the two sets of EWGSOP criteria was poor. The SARC-F questionnaire demonstrated an inherently high sensitivity (100%) as well as good specificity (75%) and diagnostic accuracy (79%) in detecting sarcopenia according to EWGSOP2 criteria.
UNASSIGNED: The prevalence rate of sarcopenia among elderly Spanish women with RA varies significantly depending on whether EWGSOP1 or EWGSOP2 criteria are applied. The SARC-F questionnaire is effective for predicting sarcopenia when used in conjunction with the EWGSOP2 criteria, which is currently the most accepted standard in clinical practice.
UNASSIGNED: In this observational, cross-sectional study, 67 women aged over 65 years who met the ACR 2010 criteria for RA were consecutively recruited from a tertiary university hospital. Assessments included: (a) demographic and anthropometric data; (b) RA-related variables (disease history, analytical evaluation, activity, disability, quality of life); and (c) sarcopenia-related variables (muscle strength, gait speed, skeletal muscle mass, and SARC-F questionnaire). The prevalence of sarcopenia was determined using both EWGSOP1 and EWGSOP2 criteria. Furthermore, the effectiveness of the SARC-F questionnaire for detecting sarcopenia were calculated.
UNASSIGNED: The prevalence of sarcopenia was 43% according to the EWGSOP1 criteria and 16% according to the EWGSOP2 criteria. Patients diagnosed with sarcopenia based on the latter criteria also met the EWGSOP1\'s criteria for sarcopenia. Agreement between the two sets of EWGSOP criteria was poor. The SARC-F questionnaire demonstrated an inherently high sensitivity (100%) as well as good specificity (75%) and diagnostic accuracy (79%) in detecting sarcopenia according to EWGSOP2 criteria.
UNASSIGNED: The prevalence rate of sarcopenia among elderly Spanish women with RA varies significantly depending on whether EWGSOP1 or EWGSOP2 criteria are applied. The SARC-F questionnaire is effective for predicting sarcopenia when used in conjunction with the EWGSOP2 criteria, which is currently the most accepted standard in clinical practice.
摘要：
■欧洲老年人肌肉减少症工作组（EWGSOP）提出了两个诊断肌肉减少症的关键建议：2010年的EWGSOP1和2019年的EWGSOP2。这些建议是目前最广泛使用的诊断肌少症的指南。然而,基于EWGSOP标准的类风湿性关节炎(RA)患者肌肉减少症患病率的数据有限.本研究旨在：（a）使用EWGSOP1和EWGSOP2标准确定西班牙老年RA女性队列中的肌肉减少症患病率；（b）评估SARC-F问卷检测肌肉减少症的有效性。
■在这次观测中，横断面研究，67名年龄在65岁以上且符合ACR2010RA标准的女性从一所三级大学医院连续招募。评估包括：（a）人口统计学和人体测量数据；（b）RA相关变量（疾病史，分析评估，活动,残疾,生活质量)；和(C)肌肉减少症相关变量(肌肉力量，步态速度,骨骼肌质量，和SARC-F问卷)。使用EWGSOP1和EWGSOP2标准确定肌肉减少症的患病率。此外，计算SARC-F问卷检测肌肉减少症的有效性.
■根据EWGSOP1标准，肌肉减少症的患病率为43％，根据EWGSOP2标准为16％。根据后一种标准诊断为肌肉减少症的患者也符合EWGSOP1的肌肉减少症标准。两组EWGSOP标准之间的协议很差。根据EWGSOP2标准，SARC-F问卷显示出固有的高灵敏度（100％）以及良好的特异性（75％）和诊断准确性（79％）。
■西班牙老年RA女性的肌少症患病率根据是否应用EWGSOP1或EWGSOP2标准而有显著差异。SARC-F问卷与EWGSOP2标准结合使用时可有效预测肌肉减少症，这是目前临床实践中最被接受的标准。
■在这次观测中，横断面研究，67名年龄在65岁以上且符合ACR2010RA标准的女性从一所三级大学医院连续招募。评估包括：（a）人口统计学和人体测量数据；（b）RA相关变量（疾病史，分析评估，活动,残疾,生活质量)；和(C)肌肉减少症相关变量(肌肉力量，步态速度,骨骼肌质量，和SARC-F问卷)。使用EWGSOP1和EWGSOP2标准确定肌肉减少症的患病率。此外，计算SARC-F问卷检测肌肉减少症的有效性.
■根据EWGSOP1标准，肌肉减少症的患病率为43％，根据EWGSOP2标准为16％。根据后一种标准诊断为肌肉减少症的患者也符合EWGSOP1的肌肉减少症标准。两组EWGSOP标准之间的协议很差。根据EWGSOP2标准，SARC-F问卷显示出固有的高灵敏度（100％）以及良好的特异性（75％）和诊断准确性（79％）。
■西班牙老年RA女性的肌少症患病率根据是否应用EWGSOP1或EWGSOP2标准而有显著差异。SARC-F问卷与EWGSOP2标准结合使用时可有效预测肌肉减少症，这是目前临床实践中最被接受的标准。
