Abstract：
As opposed to those requiring a single action for reward acquisition, tasks necessitating action sequences demand that animals learn action elements and their sequential order and sustain the behaviour until the sequence is completed. With repeated learning, animals not only exhibit precise execution of these sequences but also demonstrate enhanced smoothness and efficiency. Previous research has demonstrated that midbrain dopamine and its major projection target, the striatum, play crucial roles in these processes. Recent studies have shown that dopamine from the substantia nigra pars compacta (SNc) and the ventral tegmental area (VTA) serve distinct functions in action sequence learning. The distinct contributions of dopamine also depend on the striatal subregions, namely the ventral, dorsomedial and dorsolateral striatum. Here, we have reviewed recent findings on the role of striatal dopamine in action sequence learning, with a focus on recent rodent studies.
摘要：
与那些需要单一行动来获得奖励的人相反，需要动作序列的任务要求动物学习动作元素及其顺序顺序，并维持行为直到序列完成。随着反复学习，动物不仅表现出这些序列的精确执行，而且表现出增强的平滑性和效率。先前的研究表明，中脑多巴胺及其主要投射靶标，纹状体,在这些过程中发挥关键作用。最近的研究表明，来自黑质致密部（SNc）和腹侧被盖区（VTA）的多巴胺在动作序列学习中具有不同的功能。多巴胺的独特贡献也取决于纹状体亚区域，即腹侧，背内侧和背外侧纹状体。这里,我们回顾了纹状体多巴胺在动作序列学习中的作用的最新发现，专注于最近的啮齿动物研究。
