METHODS: Data on working hours among 22,818 workers (11,999 females) from the Korea National Health and Nutrition Examination Survey (2013-2021) were used for this study.
METHODS: MASLD was defined as a combination of hepatic steatosis combined with one or more of cardiometabolic risk factors (overweight/obesity, prediabetes/diabetes, raised blood pressure, hypertriglyceridemia, low high-density lipoprotein cholesterol). Hepatic steatosis was assessed using the hepatic steatosis index. Logistic regression was used to estimate the odds ratios (ORs) and 95% confidence intervals (CIs).
RESULTS: The overall prevalence of MASLD was 30.4% in men and 18.1% in women. Among male workers, 20.2% worked ≥55 h/week, whereas among female workers, 10.1% worked ≥55 h/week. Compared with working 35-40 h/week, working ≥55 h/week was positively associated with overweight/obesity (OR: 1.21; 95% CI: 1.05-1.40), pre-diabetes mellitus (pre-DM)/DM (OR: 1.20; 95% CI: 1.04-1.38), raised blood pressure (OR: 1.17; 95% CI: 1.02-1.35), and presence of any cardiometabolic risk factors (OR: 1.56; 95% CI: 1.21-2.02). The adjusted OR (95% CI) of the association between working hours and MASLD was 1.27 (1.09-1.47) for ≥55 h/week compared with working 35-40 h/week in male workers. In female workers, long working hours were not clearly associated with cardiometabolic risk factors and MASLD.
CONCLUSIONS: Long working hours are positively associated with MASLD among Korean male workers. Policy interventions are needed to mitigate the adverse metabolic effects of prolonged working hours.
方法:本研究使用了来自韩国国家健康和营养检查调查(2013-2021)的22,818名工人(11,999名女性)的工作时间数据。
方法:MASLD定义为肝性脂肪变性与一种或多种心脏代谢危险因素(超重/肥胖,前驱糖尿病/糖尿病,血压升高,高甘油三酯血症,低高密度脂蛋白胆固醇)。使用肝脂肪变性指数评估肝脂肪变性。Logistic回归用于估计比值比(ORs)和95%置信区间(CIs)。
结果:男性MASLD的总体患病率为30.4%,女性为18.1%。在男性工人中,20.2%工作时间≥55小时/周,而在女工中,10.1%工作时间≥55小时/周。与每周工作35-40小时相比,工作≥55小时/周与超重/肥胖呈正相关(OR:1.21;95%CI:1.05-1.40),糖尿病前期(DM前)/DM(OR:1.20;95%CI:1.04-1.38),血压升高(OR:1.17;95%CI:1.02-1.35),和存在任何心脏代谢危险因素(OR:1.56;95%CI:1.21-2.02)。与男性工人每周工作35-40小时相比,工作时间与MASLD之间的关联的校正OR(95%CI)为≥55小时/周的1.27(1.09-1.47)。在女工中,长工作时间与心脏代谢危险因素和MASLD无明显相关性.
结论:在韩国男性工人中,长时间工作时间与MASLD呈正相关。需要采取政策干预措施来减轻工作时间延长对代谢的不利影响。