Abstract:
Plant tissue culture has evolved in the last decades with several types of cultures being developed to promote a more sustainable food production system. Moreover, these cultures can be applied for the production of relevant metabolites with medicinal potential, thus contributing to nutrition and healthcare. Importantly, plant micropropagation has enabled agricultural expansion and tissue culture has emerged as a promising production alternative for several plants and their metabolites in the food, cosmetic, and pharmaceutical industries. Plant tissue cultures present several advantages over conventional propagation techniques as they are season independent, enabling a continuous supply of the plants/compounds of interest, with the guarantee of high phytosanitary quality. In addition, genetic uniformity is generally maintained, thus reducing chemical variability that can compromise safety and efficacy. Nevertheless, despite their undeniable potential, with many researchers focusing on new strategies to improve production yield in cell cultures, such as with the use of elicitors or resorting to metabolomics engineering, an effective and lucrative large-scale production has yet to be obtained. Indeed, only a few compounds with market value are produced in this regard and several limitations such as contaminations, low culture yield and production costs still need to be overcome in order to take advantage of the full potential of these techniques.
摘要:
在过去的几十年中,植物组织培养已经发展起来,开发了几种类型的培养物以促进更可持续的食品生产系统。此外,这些培养物可以用于生产具有药用潜力的相关代谢物,从而有助于营养和医疗保健。重要的是,植物微繁殖使农业扩张和组织培养成为几种植物及其代谢产物在食物中的一种有希望的生产替代品,化妆品,和制药行业。植物组织培养比传统的繁殖技术具有几个优点,因为它们与季节无关。能够连续供应感兴趣的植物/化合物,具有高植物检疫质量的保证。此外,遗传一致性总体上保持不变,从而减少可能损害安全性和功效的化学变异性。然而,尽管它们无可否认的潜力,许多研究人员专注于提高细胞培养产量的新策略,例如使用诱导子或诉诸代谢组学工程,尚未获得有效和有利可图的大规模生产。的确,在这方面只有少数具有市场价值的化合物和一些限制,如污染,低培养产量和生产成本仍然需要克服,以充分利用这些技术的潜力。