关键词: Biologics Efficacy PASI score Phototherapy Psoriasis Safety profile Treatment costs

Mesh : Humans Psoriasis / therapy drug therapy Biological Products / therapeutic use Phototherapy / methods Severity of Illness Index PUVA Therapy / methods Ultraviolet Therapy / methods

来  源:   DOI:10.1016/j.det.2024.02.002

Abstract:
Phototherapy has utility as a psoriatic therapy, given its relatively high clinical efficacy, low side effect profile, and lower cost compared to newer effective treatments like biologics and small molecules. Phototherapy has shown Psoriasis Area and Severity Index (PASI)-75 and PASI-90 rates comparable to those of biologics and small molecules, with similarly rapid onsets of action, rates of remission, and quality of life scores. Certain patients may particularly benefit from phototherapy, such as those with localized disease or contraindications to systemic immunomodulatory medication. Phototherapy can be more cost-effective than biologics and conveniently administered at home, making it a valuable therapeutic option for the right patient.
摘要:
光疗作为一种牛皮癣疗法具有实用性,鉴于其相对较高的临床疗效,低副作用简介,与生物制剂和小分子等新型有效治疗方法相比,成本更低。光疗显示银屑病面积和严重程度指数(PASI)-75和PASI-90率与生物制剂和小分子相当,随着同样快速的行动开始,缓解率,和生活质量分数。某些患者可能特别受益于光疗,如患有局部疾病或全身免疫调节药物禁忌症的患者。光疗比生物制剂更具成本效益,并且在家中方便管理,使其成为合适患者的有价值的治疗选择。
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