PDF(Pubmed)
Abstract：
Schwannomas are classified as neurogenic tumors and are the most frequent nerve sheath tumors in the paravertebral mediastinum. Recently, the addition of endobronchial ultrasound-guided intranodal forceps biopsy (EBUS-IFB) using standard-sized biopsy forceps (SBFs) to endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for metastatic lymph nodes in lung cancer patients reportedly improved the quality and quantity of the obtained specimens without significant complications. However, reports on the usefulness of this technique for benign diseases remain scarce. Here we report a case of schwannoma in the middle mediastinum, which was diagnosed by EBUS-IFB using SBFs, despite inadequate specimens obtained via EBUS-TBNA. An 80-year-old woman presented with dyspnea and a 5-cm sized middle mediastinal tumor. EBUS-TBNA and EBUS-IFB using SBFs were performed for histological diagnosis. No complications were associated with the bronchoscopy procedure, and schwannoma was solely diagnosed using the EBUS-IFB specimens. EBUS-IFB using SBFs is potentially useful for diagnosing benign diseases, including schwannomas, which are often difficult to diagnose with EBUS-TBNA.
摘要：
神经鞘瘤被归类为神经源性肿瘤，是椎旁纵隔中最常见的神经鞘瘤。最近,据报道,在肺癌患者转移性淋巴结的支气管超声引导下经支气管针吸活检术(EBUS-TBNA)基础上,使用标准大小的活检钳(SBFs)的支气管内超声引导下的结内活检钳(EBUS-IFB)提高了获得的标本的质量和数量,且无明显并发症.然而,关于这种技术对良性疾病有用性的报道仍然很少。在这里，我们报告了一个中纵隔神经鞘瘤的病例，这是通过EBUS-IFB使用SBF诊断的，尽管通过EBUS-TBNA获得的标本不足。一名80岁的女性出现呼吸困难和5厘米大小的中纵隔肿瘤。使用SBF进行EBUS-TBNA和EBUS-IFB用于组织学诊断。没有与支气管镜检查相关的并发症，神经鞘瘤仅使用EBUS-IFB标本诊断。使用SBF的EBUS-IFB可能对诊断良性疾病有用，包括神经鞘瘤,通常难以用EBUS-TBNA诊断。
