PDF(Pubmed)
Abstract：
BACKGROUND: Although parenteral nutrition (PN) significantly improves mortality rates in pediatric short bowel syndrome (SBS), long-term PN has many possible complications and impacts quality of life. Bowel lengthening procedures (BLPs) increase the contact surface of food and the intestinal mucosa and enable the better absorption of nutrients and liquids, possibly leading to a PN decrease.
METHODS: We retrospectively reviewed the data of patients with short bowel syndrome who underwent BLPs in the period from January 2016 to January 2022. Overall, eight patients, four male, five born prematurely, underwent BLPs.
RESULTS: There was a significant decrease in the percentage of total caloric intake provided via PN and PN volume after the BLPs. The more evident results were seen 6 months after the procedure and at the last follow-up, which was, on average, 31 months after the procedure. Two patients were weaned off PN after their BLPs. Patients remained well nourished during the follow-up.
CONCLUSIONS: The BLP led to a significant decrease in PN needs and an increase in the food intake; however, significant changes happened more than 6 months after the procedure.
METHODS: We retrospectively reviewed the data of patients with short bowel syndrome who underwent BLPs in the period from January 2016 to January 2022. Overall, eight patients, four male, five born prematurely, underwent BLPs.
RESULTS: There was a significant decrease in the percentage of total caloric intake provided via PN and PN volume after the BLPs. The more evident results were seen 6 months after the procedure and at the last follow-up, which was, on average, 31 months after the procedure. Two patients were weaned off PN after their BLPs. Patients remained well nourished during the follow-up.
CONCLUSIONS: The BLP led to a significant decrease in PN needs and an increase in the food intake; however, significant changes happened more than 6 months after the procedure.
摘要：
背景：尽管肠外营养（PN）可显著改善小儿短肠综合征（SBS）的死亡率，长期PN有许多可能的并发症并影响生活质量.肠道延长程序（BLPs）增加了食物和肠粘膜的接触表面，使营养和液体更好地吸收，可能导致PN下降。
方法：我们回顾性回顾了2016年1月至2022年1月期间接受BLPs治疗的短肠综合征患者的资料。总的来说,八个病人,四名男性，五个人过早出生，接受BLPs。
结果：BLP后通过PN和PN体积提供的总热量摄入百分比显着降低。更明显的结果是在手术后6个月和最后一次随访时，那是，平均而言,手术后31个月。两名患者在BLP后脱离PN。患者在随访期间保持营养良好。
结论：BLP导致PN需求的显著减少和食物摄入量的增加；然而，手术后6个月以上发生了重大变化。
方法：我们回顾性回顾了2016年1月至2022年1月期间接受BLPs治疗的短肠综合征患者的资料。总的来说,八个病人,四名男性，五个人过早出生，接受BLPs。
结果：BLP后通过PN和PN体积提供的总热量摄入百分比显着降低。更明显的结果是在手术后6个月和最后一次随访时，那是，平均而言,手术后31个月。两名患者在BLP后脱离PN。患者在随访期间保持营养良好。
结论：BLP导致PN需求的显著减少和食物摄入量的增加；然而，手术后6个月以上发生了重大变化。
