PDF(Pubmed)
Abstract：
This work presents an electrochemical sensor detecting a fungicide-azoxystrobin (AZO) in aqueous environments. This AZO sensor utilizes a thin-film metal electrode (TFME) combined with an AZO-selective molecularly imprinted polymer (AZO-MIP). The AZO-MIP was directly generated on TFME through electrochemical polymerization from the solution containing two functional monomers: aniline (Ani) and m-phenylenediamine (mPD), and the template: AZO, which was afterwards removed to form AZO-selective cavities in the polymer matrix. The AZO-MIP preparation was characterized by electrochemical and ellipsometry measurements. Optimization of the synthesis parameters, including the charge density applied during electrodeposition, the monomer-to-template ratio, was performed to enhance the sensor\'s performance. The results demonstrated that the AZO sensor achieved a low limit of detection (LOD) of 3.6 nM and a limit of quantification (LOQ) of 11.8 nM in tap water, indicating its sensitivity in a complex aqueous environment. The sensor also exhibited satisfactory selectivity for AZO in both ultrapure and tap-water samples and achieved a good recovery (94-119%) for the target analyte. This study highlights the potential of MIP-based electrochemical sensors for the rapid and accurate detection of fungicide contaminants in water, contributing to the advancement of analytical tools for water-quality monitoring and risk assessment.
摘要：
这项工作提出了一种电化学传感器，该传感器可在水性环境中检测杀菌剂-偶氮酯（AZO）。该AZO传感器利用薄膜金属电极(TFME)与AZO选择性分子印迹聚合物(AZO-MIP)组合。AZO-MIP是通过电化学聚合从含有两种功能单体的溶液直接在TFME上生成的：苯胺（Ani）和间苯二胺（mPD），和模板：AZO，然后将其除去以在聚合物基质中形成AZO选择性空穴。通过电化学和椭圆光度法测量表征AZO-MIP制备。优化合成参数，包括电沉积过程中施加的电荷密度，单体与模板的比例，执行是为了增强传感器的性能。结果表明，AZO传感器在自来水中实现了3.6nM的低检测限（LOD）和11.8nM的定量限（LOQ），表明其在复杂的水环境中的敏感性。该传感器在超纯和自来水样品中对AZO也表现出令人满意的选择性，并对目标分析物实现了良好的回收率（94-119％）。这项研究强调了基于MIP的电化学传感器用于快速准确检测水中杀菌剂污染物的潜力，促进水质监测和风险评估分析工具的发展。
