PDF(Pubmed)
Abstract：
Background/Objectives: Chronic prostatitis/chronic pelvic pain syndrome CP/CPPS is a rather common condition and in recent years many studies have shown contradictory results regarding its impact on semen quality. This prospective cohort study set out to investigate how CP/CPPS affected the parameters of semen in a prospective cohort of patients compared with the WHO 2021 reference group. Methods: From 2013 to 2022, a total of 1071 patients with suspicion of CP/CPPS received a comprehensive andrological examination. Complete semen analysis was carried out in compliance with WHO 2010 guidelines, comparing every study population semen variable to the WHO 2021 reference group (n~3500). Results: All evaluated semen parameters had median values that fell within a normal range. Nonetheless, approximately 25% of patients had values for each semen variable that were lower than the WHO reference group\'s fifth percentile. In particular, bacteriospermia was associated with a negative impact on semen volume. Conclusions: This is the largest study that compares all standard semen parameters in patients suffering from CP/CPPS to WHO 2021 reference values. It provides evidence of an impairment of conventional semen parameters.
摘要：
背景/目的：慢性前列腺炎/慢性盆腔疼痛综合征CP/CPPS是一种相当常见的疾病，近年来许多研究表明其对精液质量的影响存在矛盾的结果。这项前瞻性队列研究旨在调查与WHO2021参考组相比，CP/CPPS如何影响前瞻性队列患者的精液参数。方法:2013年至2022年,对1071例疑似CP/CPPS患者进行全面的男性检查。根据世卫组织2010年指南进行了完整的精液分析，将每个研究人群的精液变量与WHO2021参考组(n~3500)进行比较。结果：所有评估的精液参数的中值均在正常范围内。尽管如此，约25%的患者的每个精液变量值均低于WHO参考组的第5百分位数.特别是,细菌精子症对精液体积有负面影响。结论：这是一项最大的研究，将患有CP/CPPS的患者的所有标准精液参数与WHO2021参考值进行了比较。它提供了常规精液参数受损的证据。
