%0 Journal Article
%T Impaired Semen Quality in Patients with Chronic Prostatitis.
%A Rosellen J
%A Dittmar F
%A Hauptmann A
%A Diemer T
%A Schuppe HC
%A Schagdarsurengin U
%A Fritzenwanker M
%A Wagenlehner F
%A Pilatz A
%J J Clin Med
%V 13
%N 10
%D 2024 May 14
%M 38792425
%F 4.964
%R 10.3390/jcm13102884
%X Background/Objectives: Chronic prostatitis/chronic pelvic pain syndrome CP/CPPS is a rather common condition and in recent years many studies have shown contradictory results regarding its impact on semen quality. This prospective cohort study set out to investigate how CP/CPPS affected the parameters of semen in a prospective cohort of patients compared with the WHO 2021 reference group. Methods: From 2013 to 2022, a total of 1071 patients with suspicion of CP/CPPS received a comprehensive andrological examination. Complete semen analysis was carried out in compliance with WHO 2010 guidelines, comparing every study population semen variable to the WHO 2021 reference group (n~3500). Results: All evaluated semen parameters had median values that fell within a normal range. Nonetheless, approximately 25% of patients had values for each semen variable that were lower than the WHO reference group's fifth percentile. In particular, bacteriospermia was associated with a negative impact on semen volume. Conclusions: This is the largest study that compares all standard semen parameters in patients suffering from CP/CPPS to WHO 2021 reference values. It provides evidence of an impairment of conventional semen parameters.