关键词: analytical techniques biological effects extraction methods flavonoids puerarin

Mesh : Isoflavones / biosynthesis chemistry isolation & purification Humans Pueraria / chemistry Flavonoids / biosynthesis Animals

来  源:   DOI:10.3390/ijms25105222   PDF(Pubmed)

Abstract:
Flavonoids, a variety of plant secondary metabolites, are known for their diverse biological activities. Isoflavones are a subgroup of flavonoids that have gained attention for their potential health benefits. Puerarin is one of the bioactive isoflavones found in the Kudzu root and Pueraria genus, which is widely used in alternative Chinese medicine, and has been found to be effective in treating chronic conditions like cardiovascular diseases, liver diseases, gastric diseases, respiratory diseases, diabetes, Alzheimer\'s disease, and cancer. Puerarin has been extensively researched and used in both scientific and clinical studies over the past few years. The purpose of this review is to provide an up-to-date exploration of puerarin biosynthesis, the most common extraction methods, analytical techniques, and biological effects, which have the potential to provide a new perspective for medical and pharmaceutical research and development.
摘要:
黄酮类化合物,多种植物次生代谢产物,以其多样化的生物活性而闻名。异黄酮是类黄酮的一个亚类,因其潜在的健康益处而受到关注。葛根素是在葛根和葛属中发现的生物活性异黄酮之一,它被广泛用于替代中药,并被发现可以有效治疗心血管疾病等慢性病,肝脏疾病,胃病,呼吸系统疾病,糖尿病,老年痴呆症,和癌症。在过去的几年中,葛根素已被广泛研究并用于科学和临床研究。这篇综述的目的是提供葛根素生物合成的最新探索,最常见的提取方法,分析技术,和生物效应,有可能为医药研发提供新的视角。
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