Abstract:
Forty percent of Americans are obese and 20% are overweight. Until recently, notwithstanding great efforts to combat this chronic, worsening epidemic, the only therapy that \"worked\" was surgery. However, recently, a new class of safe drugs (incretins) have been developed that cause obese patients to lose ∼20 to 25% of their body weight. Herein we recount this revolution and its implications.
摘要:
40%的美国人肥胖,20%的人超重。直到最近,尽管为打击这种慢性疾病做出了巨大努力,不断恶化的流行病,唯一“有效”的疗法是手术。然而,最近,一种新的安全药物(肠促胰岛素)被开发出来,它能使肥胖患者的体重减少20%到25%。在此,我们回顾这场革命及其影响。