Abstract：
Chlorella vulgaris and Tetraselmis chuii are two microalgae species already marketed because of their richness in high-value and health-beneficial compounds. Previous studies have demonstrated the biological properties of compounds isolated from both microalgae, although data are not yet available on the impact that pre-treatment and gastrointestinal digestion could exert on these properties. The aim of the present study was to analyze the impact of the biomass pre-treatment (freeze/thaw cycles plus ultrasounds) and simulated gastrointestinal digestion in the bioaccessibility and in vitro antioxidant activity (ABTS, ORAC, Q-FRAP, Q-DPPH) of the released digests. The cell wall from microalgae were susceptible to the pre-treatment and the action of saliva and gastric enzymes, releasing bioactive peptides and phenolic compounds that contributed to the potent antioxidant activity of digests through their radical scavenging and iron reduction capacities. Our findings suggest the potential of these microalgae against oxidative stress-associated diseases at both, intestinal and systemic level.
摘要：
小球藻和Tetraselmischuii是两种已经上市的微藻物种，因为它们富含高价值和有益于健康的化合物。以前的研究已经证明了从两种微藻中分离出的化合物的生物学特性，尽管目前还没有关于治疗前和胃肠道消化可能对这些特性产生影响的数据。本研究的目的是分析生物质预处理（冷冻/解冻循环加超声波）和模拟胃肠道消化对生物可及性和体外抗氧化活性的影响（ABTS，ORAC,Q-FRAP,Q-DPPH）的发布摘要。微藻的细胞壁对预处理和唾液和胃酶的作用敏感，释放生物活性肽和酚类化合物，这些化合物通过其自由基清除和铁还原能力来促进消化物的有效抗氧化活性。我们的研究结果表明，这些微藻在这两种情况下都具有对抗氧化应激相关疾病的潜力，肠道和全身水平。
