METHODS: This retrospective analysis included patients who underwent testicular US in our department from 2018 to 2022. Inclusion criteria were: i) sufficient image quality of the stored images, ii) US with standardized SMI-default setting (colour gain of 44 ± 5), iii) patient age ≥ 18 years, and iv) normal testicular findings or testicular tumor with histopathological workup. US examinations were performed as part of clinical routine using a high-end ultrasound system (Aplio i800/i900, Canon Medical Systems Corporation, Tochigi, Japan). Statistical analysis included Chi-square test and Mann-Whitney U tests and receiver operating characteristic (ROC) curve analysis.
RESULTS: A total of 62 patients (31 each with normal findings and testicular tumors) were included. The VI differed statistically significantly (p < 0.001) between normal testis (median 2.5 %) and testicular tumors (median 17.4 %). Like vascular patterns (p < 0.001), the VI (p = 0.030) was shown to distinguish seminomas (median 14.8 %), non-seminomas (median 17.6 %) and lymphomas (median 34.5 %).
CONCLUSIONS: In conclusion, our study has shown the VI to be a quantitative tool that can add information for differentiating testicular tumor entities. While further confirmation in larger study populations is desirable, our results suggest that the VI may be a useful quantitative parameter.
方法:这项回顾性分析包括2018年至2022年在我科接受睾丸US检查的患者。纳入标准是:i)存储图像的足够图像质量,ii)美国标准SMI默认设置(颜色增益为44±5),iii)患者年龄≥18岁,和iv)正常睾丸发现或睾丸肿瘤与组织病理学检查。作为临床常规的一部分,使用高端超声系统(Aplioi800/i900,佳能医疗系统公司,Tochigi,日本)。统计分析包括卡方检验和Mann-WhitneyU检验以及受试者工作特征(ROC)曲线分析。
结果:共纳入62例患者(31例患者均表现正常,睾丸肿瘤)。正常睾丸(中位数为2.5%)和睾丸肿瘤(中位数为17.4%)之间的VI统计学差异显着(p<0.001)。像血管模式(p<0.001),VI(p=0.030)显示可区分精原细胞瘤(中位数14.8%),非精原细胞瘤(中位数17.6%)和淋巴瘤(中位数34.5%)。
结论:结论:我们的研究表明,VI是一种定量工具,可以增加区分睾丸肿瘤实体的信息。虽然需要在更大的研究人群中进一步确认,我们的结果表明,VI可能是一个有用的定量参数。