关键词: carbon monoxide intoxication hyperbaric oxygen therapy peripheral neuropathy rehabilitation training spinal cord ischemia

来  源:   DOI:10.3389/fneur.2024.1346353   PDF(Pubmed)

Abstract:
Carbon monoxide (CO) is a gas that has no odor or color, making it difficult to detect until exposure leads to coma or death. CO poisoning is one of the most common and deadly poisonings around the world. CO poisoning is a common and often fatal form of poisoning worldwide. A toxic effect of CO is tissue hypoxia, which leads to systemic complications. Additionally, there may be severe neurological symptoms and delayed complications following CO poisoning. However, peripheral neuropathy is relatively rare after CO poisoning. Previously, only one case of unilateral plexopathy after CO poisoning, accompanied by rhabdomyolysis and cognitive dysfunction, has been reported. In this report, an isolated unilateral brachial plexopathy following CO intoxication is described. A key mechanism in this case may be CO-induced spinal cord ischemia. Immediate administration of hyperbaric oxygen therapy (HBOT) is crucial to prevent peripheral neuropathy after acute CO intoxication. Hyperbaric oxygen therapy (HBOT) should be administered immediately after acute CO intoxication to prevent peripheral neuropathy. Additionally, peripheral neuropathy following acute CO intoxication may benefit from consistent rehabilitation training.
摘要:
一氧化碳(CO)是一种没有气味或颜色的气体,在暴露导致昏迷或死亡之前很难发现。一氧化碳中毒是世界上最常见和最致命的中毒之一。一氧化碳中毒是全球常见且通常致命的中毒形式。CO的毒性作用是组织缺氧,导致全身并发症.此外,一氧化碳中毒后可能出现严重的神经系统症状和迟发性并发症.然而,CO中毒后周围神经病变相对罕见。以前,只有一例一氧化碳中毒后的单侧神经丛病变,伴有横纹肌溶解和认知功能障碍,已被报道。在这份报告中,描述了一氧化碳中毒后孤立的单侧臂丛神经病变。这种情况下的关键机制可能是CO诱导的脊髓缺血。立即给予高压氧治疗(HBOT)对于预防急性CO中毒后的周围神经病变至关重要。急性CO中毒后应立即进行高压氧治疗(HBOT),以预防周围神经病变。此外,急性一氧化碳中毒后的周围神经病变可能受益于持续的康复训练.
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