PDF(Pubmed)
Abstract：
OBJECTIVE: The goal of epilepsy treatment is not only to control convulsive seizures but also to improve the quality of life of patients. This study aimed to investigate personality changes and the risk factors for their development in adult epilepsy patients.
METHODS: A case-control study in a Class III, Class A hospital. The study comprised 206 adult epilepsy patients admitted to the Neurology Department at the First Hospital of Jilin University between October 2019 and December 2021, while the control group consisted of 154 community volunteers matched with the epilepsy group based on age, sex, and education. No additional treatment interventions were determined to be relevant in the context of this study.
RESULTS: There is a significantly higher incidence of personality changes in epilepsy than in the general population, and patients with epilepsy were more likely to become psychoticism, neuroticism, and lie. Epilepsy patient\'s employment rate and average quality of life score were significantly lower than that of the general population and had strong family intimacy but poor adaptability in this study. There are many factors affecting personality change: sleep disorders, economic status, quality of life, use of anti-seizure drugs, family cohesion and adaptability. The independent risk factors were quality of life and family cohesion.
METHODS: A case-control study in a Class III, Class A hospital. The study comprised 206 adult epilepsy patients admitted to the Neurology Department at the First Hospital of Jilin University between October 2019 and December 2021, while the control group consisted of 154 community volunteers matched with the epilepsy group based on age, sex, and education. No additional treatment interventions were determined to be relevant in the context of this study.
RESULTS: There is a significantly higher incidence of personality changes in epilepsy than in the general population, and patients with epilepsy were more likely to become psychoticism, neuroticism, and lie. Epilepsy patient\'s employment rate and average quality of life score were significantly lower than that of the general population and had strong family intimacy but poor adaptability in this study. There are many factors affecting personality change: sleep disorders, economic status, quality of life, use of anti-seizure drugs, family cohesion and adaptability. The independent risk factors were quality of life and family cohesion.
摘要：
目的：癫痫治疗的目标不仅是控制惊厥性癫痫发作，而且是提高患者的生活质量。本研究旨在探讨成人癫痫患者的人格变化及其发展的危险因素。
方法：一项III级病例对照研究，甲级医院。该研究包括2019年10月至2021年12月在吉林大学第一医院神经内科住院的206名成年癫痫患者，而对照组由154名社区志愿者组成，根据年龄与癫痫组相匹配。性别,和教育。在本研究的背景下，没有确定其他治疗干预措施是相关的。
结果：癫痫的人格改变发生率明显高于普通人群，癫痫患者更容易成为精神病患者，神经质,和谎言。本研究癫痫患者的就业率和平均生活质量评分明显低于一般人群,且家庭亲密度强,但适应性差。影响人格改变的因素很多：睡眠障碍，经济地位,生活质量,使用抗癫痫药物，家庭凝聚力和适应能力。独立危险因素为生活质量和家庭亲密度。
方法：一项III级病例对照研究，甲级医院。该研究包括2019年10月至2021年12月在吉林大学第一医院神经内科住院的206名成年癫痫患者，而对照组由154名社区志愿者组成，根据年龄与癫痫组相匹配。性别,和教育。在本研究的背景下，没有确定其他治疗干预措施是相关的。
结果：癫痫的人格改变发生率明显高于普通人群，癫痫患者更容易成为精神病患者，神经质,和谎言。本研究癫痫患者的就业率和平均生活质量评分明显低于一般人群,且家庭亲密度强,但适应性差。影响人格改变的因素很多：睡眠障碍，经济地位,生活质量,使用抗癫痫药物，家庭凝聚力和适应能力。独立危险因素为生活质量和家庭亲密度。
