PDF(Pubmed)
Abstract：
Indigenous communities in Brazil have a complex epidemiological profile, which increases their chances of contracting sexually transmitted diseases. However, limited data is available on Treponema pallidum infections in this population. We investigated the seroprevalence and risk factors associated with T. pallidum infection in an indigenous population of Dourados, Mato Grosso do Sul. Blood samples were collected from September 2017 to March 2020, and the participants were interviewed to obtain comprehensive data on demography and sexual behavior. Serological tests were performed to detect T. pallidum infection. Besides conducting descriptive analysis, we performed Chi-squared tests and determined the bivariate odds ratio. The data were also analyzed using logistic regression. Among the 2190 invited individuals, 1927 (88%) were included in this study. The seroprevalence of T. pallidum infection was 2.91%. The results of a multivariate analysis showed that individuals who were 30-39 years old, with up to 4 years of school education, living in households without piped water, with a history of genital lesions, multiple sexual partners, and having a history of STIs had the highest seroprevalence of T. pallidum. This study showed that behavioral, social, and economic factors play an important role in the transmission of T. pallidum within the indigenous population. Thus, targeted intervention, including imparting education in the native language, mass testing initiatives, and implementing public policies to improve socioeconomic indicators, is needed to reduce the cases of syphilis in this community.
摘要：
巴西的土著社区有着复杂的流行病学特征，这增加了他们感染性传播疾病的机会。然而,关于该人群梅毒螺旋体感染的数据有限.我们调查了Dourados土著居民中与梅毒螺旋体感染相关的血清阳性率和危险因素，南马托格罗索州。从2017年9月至2020年3月收集血液样本，并对参与者进行了访谈，以获得有关人口统计学和性行为的综合数据。进行血清学测试以检测梅毒螺旋体感染。除了进行描述性分析，我们进行了卡方检验并确定了双变量比值比.还使用逻辑回归分析数据。在2190名受邀人士中，1927年（88%）被纳入本研究。梅毒螺旋体感染的血清阳性率为2.91%。多变量分析结果显示,30-39岁的个体,长达4年的学校教育，生活在没有自来水的家庭中，有生殖器病变史,多个性伴侣,有性传播感染史的梅毒螺旋体血清阳性率最高。这项研究表明，行为，社会,和经济因素在梅毒螺旋体在土著人口中的传播中起着重要作用。因此，有针对性的干预,包括以母语进行教育，大规模测试计划，实施改善社会经济指标的公共政策，需要减少这个社区的梅毒病例。
