PDF(Pubmed)
Abstract：
Despite accumulating evidence that blood flow restriction (BFR) training promotes muscle hypertrophy and strength gain, the underlying neurophysiological mechanisms have rarely been explored. The primary goal of this study is to investigate characteristics of cerebral cortex activity during BFR training under different pressure intensities. 24 males participated in 30% 1RM squat exercise, changes in oxygenated hemoglobin concentration (HbO) in the primary motor cortex (M1), pre-motor cortex (PMC), supplementary motor area (SMA), and dorsolateral prefrontal cortex (DLPFC), were measured by fNIRS. The results showed that HbO increased from 0 mmHg (non-BFR) to 250 mmHg but dropped sharply under 350 mmHg pressure intensity. In addition, HbO and functional connectivity were higher in M1 and PMC-SMA than in DLPFC. Moreover, the significant interaction effect between pressure intensity and ROI for HbO revealed that the regulation of cerebral cortex during BFR training was more pronounced in M1 and PMC-SMA than in DLPFC. In conclusion, low-load resistance training with BFR triggers acute responses in the cerebral cortex, and moderate pressure intensity achieves optimal neural benefits in enhancing cortical activation. M1 and PMC-SMA play crucial roles during BFR training through activation and functional connectivity regulation.
摘要：
尽管越来越多的证据表明血流限制（BFR）训练促进肌肉肥大和力量增加，基本的神经生理机制很少被探索。本研究的主要目的是研究不同压力强度下BFR训练过程中大脑皮层活动的特征。24名男性参加了30%1RM深蹲运动，初级运动皮质（M1）中氧合血红蛋白浓度（HbO）的变化，运动前皮层（PMC），辅助电机区域（SMA），和背外侧前额叶皮质（DLPFC），通过fNIRS测量。结果表明，HbO从0mmHg（非BFR）增加到250mmHg，但在350mmHg的压力强度下急剧下降。此外,M1和PMC-SMA的HbO和功能连通性高于DLPFC。此外，HbO的压力强度与ROI之间的显着交互作用表明，M1和PMC-SMA在BFR训练期间对大脑皮层的调节比DLPFC更明显。总之,使用BFR的低负荷阻力训练会触发大脑皮层的急性反应，和适度的压力强度在增强皮层激活方面实现了最佳的神经益处。M1和PMC-SMA通过激活和功能连接调节在BFR训练中发挥关键作用。
