PDF(Pubmed)
Abstract：
BACKGROUND: Neonatal sepsis is one of the most common causes of disease and death among neonates globally. And it made a great contribution to neonatal admission to intensive care units. To mitigate the ongoing neonatal crisis and accomplish the goal of sustainable development through a decrease in neonatal mortality, information from various regions is needed. Despite the considerable burden of neonatal sepsis in our setting, no prior studies were conducted in the study area. So, this study aimed to assess the magnitude and associated factors of neonatal sepsis among neonates admitted to the neonatal intensive care unit at Hawassa University Comprehensive Specialized Hospital, Sidama Regional State, Ethiopia.
METHODS: A hospital-based cross-sectional study was carried out among 287 neonates from March 1, 2020, to April 25, 2020. An interviewer-administered structured questionnaire was used to collect the data. The data were cleaned, coded, and entered into Epi Data 3.1 software and exported to Statistical Package for Social Science (SPSS) software version 23.0 for analysis. Binary logistic regression analyses were performed to identify variables having a significant association with neonatal sepsis. A p-value of ≤ 0.05 was considered statistically significant during multivariable logistic regression.
RESULTS: The study found that the magnitude of neonatal sepsis was 56%. The mean age of neonates was 3.2(SD±2.2) days. Around two-fifths (39%) of neonates were in the gestational age of <37 completed weeks. A quarter of mothers(25.8%) were delivered through cesarean section. During labor, 251 (87.5%) mothers had ≤4 digital vaginal examinations. Moreover, the finding revealed that mothers who delivered by cesarean section [AOR = 2.13, 95% CI (1.090-4.163)]. neonates who had been resuscitated at birth [AOR = 4.5, 95% CI (2.083-9.707)], and neonates who had NG tube inserted [AOR = 4.29, 95% CI (2.302-8.004)] were found to be significantly associated with neonatal sepsis.
CONCLUSIONS: The current study shows that neonatal sepsis was prevalent among more than half of the neonates admitted to the NICU. Therefore, designing strategies to enhance the aseptic techniques of professionals in the provision of care and actively and collaboratively working with cluster health facilities is highly recommended.
METHODS: A hospital-based cross-sectional study was carried out among 287 neonates from March 1, 2020, to April 25, 2020. An interviewer-administered structured questionnaire was used to collect the data. The data were cleaned, coded, and entered into Epi Data 3.1 software and exported to Statistical Package for Social Science (SPSS) software version 23.0 for analysis. Binary logistic regression analyses were performed to identify variables having a significant association with neonatal sepsis. A p-value of ≤ 0.05 was considered statistically significant during multivariable logistic regression.
RESULTS: The study found that the magnitude of neonatal sepsis was 56%. The mean age of neonates was 3.2(SD±2.2) days. Around two-fifths (39%) of neonates were in the gestational age of <37 completed weeks. A quarter of mothers(25.8%) were delivered through cesarean section. During labor, 251 (87.5%) mothers had ≤4 digital vaginal examinations. Moreover, the finding revealed that mothers who delivered by cesarean section [AOR = 2.13, 95% CI (1.090-4.163)]. neonates who had been resuscitated at birth [AOR = 4.5, 95% CI (2.083-9.707)], and neonates who had NG tube inserted [AOR = 4.29, 95% CI (2.302-8.004)] were found to be significantly associated with neonatal sepsis.
CONCLUSIONS: The current study shows that neonatal sepsis was prevalent among more than half of the neonates admitted to the NICU. Therefore, designing strategies to enhance the aseptic techniques of professionals in the provision of care and actively and collaboratively working with cluster health facilities is highly recommended.
摘要：
背景：新生儿败血症是全球新生儿中最常见的疾病和死亡原因之一。它为新生儿进入重症监护病房做出了巨大贡献。减轻持续的新生儿危机，并通过降低新生儿死亡率实现可持续发展的目标，需要来自不同地区的信息。尽管新生儿败血症在我们的环境中有相当大的负担，之前没有在研究区域进行研究.所以,这项研究旨在评估Hawassa大学综合专科医院新生儿重症监护病房新生儿败血症的程度和相关因素，西达玛地区州，埃塞俄比亚。
方法：从2020年3月1日至2020年4月25日，对287例新生儿进行了基于医院的横断面研究。使用面试官管理的结构化问卷来收集数据。数据被清理了,编码,并输入EpiData3.1软件，导出到社会科学统计软件包（SPSS）软件版本23.0进行分析。进行二元逻辑回归分析以确定与新生儿败血症有显著关联的变量。在多变量逻辑回归中，p值≤0.05被认为具有统计学意义。
结果：研究发现新生儿败血症的程度为56％。新生儿的平均年龄为3.2（SD±2.2）天。大约五分之二（39%）的新生儿的胎龄小于37周。四分之一的母亲（25.8％）通过剖宫产分娩。在劳动期间,251例（87.5%）母亲进行了≤4次阴道指检。此外，该发现显示,剖宫产分娩的母亲[AOR=2.13,95%CI(1.090-4.163)].出生时复苏的新生儿[AOR=4.5,95%CI(2.083-9.707)],发现插入NG管的新生儿[AOR=4.29，95％CI（2.302-8.004）]与新生儿败血症显着相关。
结论：目前的研究表明，新生儿败血症在NICU收治的新生儿中占一半以上。因此,强烈建议设计策略，以提高专业人员在提供护理方面的无菌技术，并积极与集群医疗机构合作。
方法：从2020年3月1日至2020年4月25日，对287例新生儿进行了基于医院的横断面研究。使用面试官管理的结构化问卷来收集数据。数据被清理了,编码,并输入EpiData3.1软件，导出到社会科学统计软件包（SPSS）软件版本23.0进行分析。进行二元逻辑回归分析以确定与新生儿败血症有显著关联的变量。在多变量逻辑回归中，p值≤0.05被认为具有统计学意义。
结果：研究发现新生儿败血症的程度为56％。新生儿的平均年龄为3.2（SD±2.2）天。大约五分之二（39%）的新生儿的胎龄小于37周。四分之一的母亲（25.8％）通过剖宫产分娩。在劳动期间,251例（87.5%）母亲进行了≤4次阴道指检。此外，该发现显示,剖宫产分娩的母亲[AOR=2.13,95%CI(1.090-4.163)].出生时复苏的新生儿[AOR=4.5,95%CI(2.083-9.707)],发现插入NG管的新生儿[AOR=4.29，95％CI（2.302-8.004）]与新生儿败血症显着相关。
结论：目前的研究表明，新生儿败血症在NICU收治的新生儿中占一半以上。因此,强烈建议设计策略，以提高专业人员在提供护理方面的无菌技术，并积极与集群医疗机构合作。
