Abstract：
BACKGROUND: People with intellectual/developmental disabilities (IDD) are known to have high rates of prescription drug use, particularly for psychotropic medications. This is of concern due to the many side effects associated with these medications and because of the risks of polypharmacy. In this paper we compare the most commonly dispensed drugs and all psychotropic medications for youth with IDD compared with youth without IDD.
METHODS: Using population-level administrative health data over a 10-year period, this study examined medications dispensed to youth with an IDD aged 15-24 years compared with youth without an IDD. The most common medications dispensed and the number of youth they were dispensed to were determined. As well a wide variety of psychotropic medications were examined.
RESULTS: There were a total of 20 591 youth with IDD and 1 293 791 youth without IDD identified. Youth with IDD had higher odds of being dispensed pain medications, amoxicillin, salbutamol, levothyroxine and all the psychotropic medications (antidepressants, antipsychotics, anxiolytics, anti-adrenergic agents, mood stabilisers and stimulants). For youth with IDD, 6558 (31.85%) were dispensed two or more different psychotropic medications within a year, compared with 75 963 (5.87%) of youth without IDD.
CONCLUSIONS: Compared to youth without IDD, youth with IDD had significantly higher odds of being dispensed most of the prescription medications studied, including all of the psychotropic medications. They were also twice as likely to be dispensed two or more medications from different classes of psychotropic drugs within the same year. These findings have important implications for the health of people with IDD and for their health care providers.
METHODS: Using population-level administrative health data over a 10-year period, this study examined medications dispensed to youth with an IDD aged 15-24 years compared with youth without an IDD. The most common medications dispensed and the number of youth they were dispensed to were determined. As well a wide variety of psychotropic medications were examined.
RESULTS: There were a total of 20 591 youth with IDD and 1 293 791 youth without IDD identified. Youth with IDD had higher odds of being dispensed pain medications, amoxicillin, salbutamol, levothyroxine and all the psychotropic medications (antidepressants, antipsychotics, anxiolytics, anti-adrenergic agents, mood stabilisers and stimulants). For youth with IDD, 6558 (31.85%) were dispensed two or more different psychotropic medications within a year, compared with 75 963 (5.87%) of youth without IDD.
CONCLUSIONS: Compared to youth without IDD, youth with IDD had significantly higher odds of being dispensed most of the prescription medications studied, including all of the psychotropic medications. They were also twice as likely to be dispensed two or more medications from different classes of psychotropic drugs within the same year. These findings have important implications for the health of people with IDD and for their health care providers.
摘要：
背景：已知智力/发育障碍（IDD）患者的处方药使用率很高，特别是精神药物。由于与这些药物相关的许多副作用以及多重用药的风险，这是令人担忧的。在本文中，我们比较了患有IDD的年轻人与没有IDD的年轻人的最常用分配药物和所有精神药物。
方法：使用10年期间的人口级行政卫生数据，这项研究调查了与未患有IDD的青少年相比,向15~24岁患有IDD的青少年分配的药物.确定了分配的最常见药物和分配给他们的青年人数。还检查了各种各样的精神药物。
结果：共有20.591名患有IDD的青年和1.293.791名没有IDD的青年。患有IDD的年轻人被分配止痛药的几率更高，阿莫西林,沙丁胺醇,左甲状腺素和所有的精神药物（抗抑郁药，抗精神病药,抗焦虑药,抗肾上腺素药,情绪稳定剂和兴奋剂)。对于患有IDD的年轻人来说，6558人(31.85%)在一年内配发两种或两种以上不同的精神药物,与无IDD青年的75.963（5.87％）相比。
结论：与没有缺碘症的年轻人相比，患有IDD的年轻人被分配大多数研究的处方药的几率明显更高，包括所有的精神药物。在同一年内，他们从不同类别的精神药物中分配两种或多种药物的可能性也是原来的两倍。这些发现对IDD患者及其医疗保健提供者的健康具有重要意义。
方法：使用10年期间的人口级行政卫生数据，这项研究调查了与未患有IDD的青少年相比,向15~24岁患有IDD的青少年分配的药物.确定了分配的最常见药物和分配给他们的青年人数。还检查了各种各样的精神药物。
结果：共有20.591名患有IDD的青年和1.293.791名没有IDD的青年。患有IDD的年轻人被分配止痛药的几率更高，阿莫西林,沙丁胺醇,左甲状腺素和所有的精神药物（抗抑郁药，抗精神病药,抗焦虑药,抗肾上腺素药,情绪稳定剂和兴奋剂)。对于患有IDD的年轻人来说，6558人(31.85%)在一年内配发两种或两种以上不同的精神药物,与无IDD青年的75.963（5.87％）相比。
结论：与没有缺碘症的年轻人相比，患有IDD的年轻人被分配大多数研究的处方药的几率明显更高，包括所有的精神药物。在同一年内，他们从不同类别的精神药物中分配两种或多种药物的可能性也是原来的两倍。这些发现对IDD患者及其医疗保健提供者的健康具有重要意义。
