Abstract：
The utilization of fluorescent quantum dots (FL QDs) has gained significant traction in the realm of antibiotic detection, owing to their exceptional FL properties and versatility. Various types of QDs have been tailored to exhibit superior FL characteristics, employing diverse capping agents such as metals, surfactants, polymers, and biomass to protect and stabilize their surfaces. In their evolution, FL QDs have demonstrated both \"turn-off\" and \"turn-on\" mechanisms in response to the presence of analytes, offering promising avenues for biosensing applications. This review article provides a comprehensive overview of the recent advancements in antibiotic detection utilizing FL QDs as biosensors. It encompasses an extensive examination of different types of FL QDs, including carbon, metal, and core-shell QDs, deployed for the detection of antibiotics. Furthermore, the synthesis methods employed for the fabrication of various FL QDs are elucidated, shedding light on the diverse approaches adopted in their preparation. Moreover, this review delves into the intricate sensing mechanisms underlying FL QDs-based antibiotic detection. Various mechanisms, such as photoinduced electron transfer, electron transfer, charge transfer, Forster resonance energy transfer, static quenching, dynamic quenching, inner filter effect, hydrogen bonding, and aggregation-induced emission, are discussed in detail. These mechanisms provide a robust scientific rationale for the detection of antibiotics using FL QDs, showcasing their potential for sensitive and selective sensing applications. Finally, the review addresses current challenges and offers perspectives on the future improvement of FL QDs in sensing applications. Insights into overcoming existing limitations and harnessing emerging technologies are provided, charting a course for the continued advancement of FL QDs-based biosensing platforms in the field of antibiotic detection.
摘要：
荧光量子点（FL量子点）的利用在抗生素检测领域获得了显著的牵引力，由于其特殊的FL性能和多功能性。各种类型的QD已被定制以表现出优异的FL特性，采用不同的封端剂，如金属，表面活性剂，聚合物，和生物质来保护和稳定它们的表面。在他们的进化中,FLQD已经证明了响应分析物存在的“关闭”和“打开”机制，为生物传感应用提供了有希望的途径。这篇综述文章全面概述了利用FLQDs作为生物传感器进行抗生素检测的最新进展。它包括对不同类型的FLQD的广泛检查，包括碳,金属,和核壳量子点，部署用于检测抗生素。此外，阐明了用于制造各种FLQD的合成方法，阐明在准备工作中采用的各种方法。此外，这篇综述探讨了基于FLQDs的抗生素检测的复杂传感机制。各种机制,如光诱导电子转移，电子转移,电荷转移,福斯特共振能量转移，静态淬火,动态淬火,内部过滤效果，氢键,和聚集诱导的排放，详细讨论。这些机制为使用FLQD检测抗生素提供了强有力的科学依据，展示了他们的敏感和选择性传感应用的潜力。最后,该综述解决了当前的挑战，并提出了未来FLQD在传感应用中的改进观点。提供了克服现有限制和利用新兴技术的见解，为基于FLQDs的生物传感平台在抗生素检测领域的持续发展制定了路线。
