Abstract：
UNASSIGNED: Tuberculosis (TB) remains a significant global health concern and kills millions of people every year. While TB can affect any organ in the body, breast TB is relatively uncommon. This study presents a comprehensive review of literature spanning 23 years, with a focus on cases of breast TB in Iran. Among the 96 cases found, the majority (89.6%) fell within the age range of 20-60, with a striking prevalence among women (98.9%). Common symptoms included pain and palpable mass, each presenting in approximately 60.4% of cases. Notably, only a quarter of patients had a confirmed history of exposure to a known TB case. Left breast involvement was more prevalent (58.3%), with ipsilateral lymph node enlargement observed in 40.6% of cases. Given the clinical presentation of breast TB, which often leads to misdiagnosis, a significant proportion of cases (68.7%) were diagnosed through excisional biopsy. Following a standard 6-month regimen of anti-TB drugs, relapse occurred in only 4.2% of cases. This study highlights the need for heightened awareness and vigilance in diagnosing breast TB, especially in regions with a high burden. Although breast TB poses diagnostic challenges, with prompt identification and treatment, the prognosis is generally favorable, with a low incidence of relapse.
摘要：
结核病(TB)仍然是一个重要的全球健康问题，每年导致数百万人死亡。虽然结核病可以影响身体的任何器官，乳腺结核比较少见.本研究对23年的文献进行了全面的回顾，重点关注伊朗的乳腺结核病例。在发现的96例病例中，大多数(89.6%)落在20-60岁的年龄范围内,女性患病率惊人(98.9%).常见症状包括疼痛和明显的肿块，每个病例约占60.4%。值得注意的是,只有1/4的患者有已知TB病例的确诊暴露史.左乳房受累更为普遍（58.3％），40.6%的病例伴有同侧淋巴结肿大。鉴于乳腺结核的临床表现，这往往会导致误诊，相当比例的病例(68.7%)是通过切除活检确诊的.在标准的6个月抗结核药物治疗方案之后，只有4.2%的病例出现复发.这项研究强调了在诊断乳腺结核病时需要提高意识和警惕性。特别是在高负担地区。虽然乳腺结核带来了诊断挑战，及时识别和治疗，预后总体良好，复发率低。
