Abstract：
UNASSIGNED: We investigated the effect of Remote Ischemic Preconditioning (RIPC) on the inflammatory response during CPB by means of serum presepsin levels at preoperative and postoperative 1st and 24th h.
UNASSIGNED: In this prospective, randomized, cross-sectional study we included 81 patients undergoing coronary artery bypass graft surgery with cardiopulmonary bypass (CPB). Patients were randomized and RIPC was applied to 40 patients in the study group before anesthesia. The remaining 41 patients were determined as the control group. The relationships between RIPC and factors such as presepsin, C-reactive protein (CRP), and leukocyte levels were investigated.
UNASSIGNED: There was no significant difference between the groups in postoperative leukocyte and CRP values (p = 0.52, p = 0.13, respectively). When the preoperative and postoperative first hour presepsin values of the patients were compared, no significant difference was found in the control group (p = 0.17), but a significant difference was found in the study group (p < 0.05). When the presepsin values were compared between the groups, a significant difference was found only in the postoperative first hour value (p < 0.05).
UNASSIGNED: It was observed that RIPC application caused to increase the presepsin levels in the postoperative first hour significantly in the study group (p < 0.05).
UNASSIGNED: In this prospective, randomized, cross-sectional study we included 81 patients undergoing coronary artery bypass graft surgery with cardiopulmonary bypass (CPB). Patients were randomized and RIPC was applied to 40 patients in the study group before anesthesia. The remaining 41 patients were determined as the control group. The relationships between RIPC and factors such as presepsin, C-reactive protein (CRP), and leukocyte levels were investigated.
UNASSIGNED: There was no significant difference between the groups in postoperative leukocyte and CRP values (p = 0.52, p = 0.13, respectively). When the preoperative and postoperative first hour presepsin values of the patients were compared, no significant difference was found in the control group (p = 0.17), but a significant difference was found in the study group (p < 0.05). When the presepsin values were compared between the groups, a significant difference was found only in the postoperative first hour value (p < 0.05).
UNASSIGNED: It was observed that RIPC application caused to increase the presepsin levels in the postoperative first hour significantly in the study group (p < 0.05).
摘要：
■我们通过术前和术后第1小时和第24小时的血清presepsin水平研究了远程缺血预处理（RIPC）对CPB期间炎症反应的影响。
■在这个前景中，随机化，横断面研究我们纳入了81例接受体外循环(CPB)冠状动脉旁路移植术的患者.将患者随机分组，并在麻醉前对研究组中的40名患者应用RIPC。其余41例患者作为对照组。RIPC与presepsin等因素之间的关系，C反应蛋白(CRP),和白细胞水平进行了调查。
■术后白细胞和CRP值在各组之间没有显着差异（分别为p=0.52，p=0.13）。比较患者术前和术后第1小时Presepsin值,对照组无显著差异(p=0.17)，但研究组差异有统计学意义(p<0.05)。当两组之间比较presepsin值时，仅在术后第1小时值有显著性差异(p<0.05)。
■观察到，在研究组中，RIPC应用导致术后第一小时的presepsin水平显着增加（p<0.05）。
■在这个前景中，随机化，横断面研究我们纳入了81例接受体外循环(CPB)冠状动脉旁路移植术的患者.将患者随机分组，并在麻醉前对研究组中的40名患者应用RIPC。其余41例患者作为对照组。RIPC与presepsin等因素之间的关系，C反应蛋白(CRP),和白细胞水平进行了调查。
■术后白细胞和CRP值在各组之间没有显着差异（分别为p=0.52，p=0.13）。比较患者术前和术后第1小时Presepsin值,对照组无显著差异(p=0.17)，但研究组差异有统计学意义(p<0.05)。当两组之间比较presepsin值时，仅在术后第1小时值有显著性差异(p<0.05)。
■观察到，在研究组中，RIPC应用导致术后第一小时的presepsin水平显着增加（p<0.05）。
