Abstract：
Avian eggshells exhibit excellent antimicrobial properties. In this study, we conducted simulation experiments to explore the defense mechanisms of eggshell membranes with regards to their physical features. We developed a mathematical model for the movement of microorganisms and estimated their penetration ratio into eggshell membranes based on several factors, including membrane thickness, microbial size, directional drift, and attachment probability to membrane fibers. These results not only suggest that an eggshell membrane with multiple layers and low porosity indicates high antimicrobial performance, but also imply that the fibrous network structure of the membrane might contribute to effective defense. Our simulation results aligned with experimental findings, specifically in measuring the penetration time of Escherichia coli through the eggshell membrane. We briefly discuss the significance and limitations of this pilot study, as well as the potential for these results, to serve as a foundation for the development of antimicrobial materials.
摘要：
禽类蛋壳表现出优异的抗菌性能。在这项研究中,我们进行了模拟实验，以探索蛋壳膜的防御机制，关于其物理特征。我们建立了微生物运动的数学模型，并根据几个因素估算了它们进入蛋壳膜的渗透率，包括膜厚度，微生物的大小，定向漂移,和附着到膜纤维的可能性。这些结果不仅表明，具有多层和低孔隙率的蛋壳膜表明高抗菌性能，但也暗示膜的纤维网络结构可能有助于有效的防御。我们的模拟结果与实验结果一致，特别是在测量大肠杆菌通过蛋壳膜的渗透时间。我们简要讨论了这项试点研究的意义和局限性，以及这些结果的潜力，作为抗菌材料发展的基础。
