关键词: Fungal orbital cellulitis case report histopathology immunocompromised patient orbital aspergillosis orbital tumor

Mesh : Humans Male Middle Aged Aspergillosis / diagnosis complications microbiology immunology Immunocompromised Host Tomography, X-Ray Computed Antifungal Agents / therapeutic use Orbital Cellulitis / microbiology diagnosis Debridement Eye Infections, Fungal / diagnosis microbiology

来  源:   DOI:10.1177/03000605241239857   PDF(Pubmed)

Abstract:
Fungal orbital cellulitis is usually seen in immunocompromised individuals, and opportunistic pathogens are the main etiology. We herein report a case of fungal orbital cellulitis due to Aspergillus in a patient with no history of trauma. A 48-year-old man presented to the emergency room of our hospital with a 2-week history of periorbital swelling, conjunctival hyperemia, and chemosis of his right eye. The visual acuity of his right eye was 6/20, and the intraocular pressure was 44 mmHg. The main clinical findings were proptosis of the right ocular globe with conjunctival hyperemia and a palpable infratemporal orbital mass. Laboratory testing failed to detect the presence of a pathogenic infection, and the lesions on computed tomography images resembled those of a malignant tumor of the orbit. The diagnosis was finally confirmed by postoperative pathological examination, and the patient responded favorably to debridement combined with antifungal therapy. Histopathological examination may help to reveal the nature of this disease. Surgical removal of inflammatory lesions can serve as an important diagnostic and treatment method for fungal orbital cellulitis.
摘要:
真菌性眼眶蜂窝织炎通常见于免疫受损的个体,和机会性病原体是主要的病因。我们在此报告一例无外伤史的患者因曲霉菌引起的真菌性眼眶蜂窝织炎。一名48岁的男子出现在我院急诊室,有2周的眶周肿胀病史,结膜充血,和他右眼的化学.他的右眼视力为6/20,眼压为44mmHg。主要临床表现为右眼球突出伴结膜充血和可触及的颞下眶肿块。实验室检测未能发现病原体感染的存在,计算机断层扫描图像上的病变类似于眼眶的恶性肿瘤。最终经术后病理检查确诊,患者对清创术联合抗真菌治疗反应良好。组织病理学检查可能有助于揭示这种疾病的性质。手术切除炎性病变可作为真菌性眼眶蜂窝织炎的重要诊断和治疗方法。
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