PDF(Pubmed)
Abstract：
Volatile organic compounds (VOCs) are chemicals emitted as products of cell metabolism, which reflects the physiological and pathological conditions of any living organisms. These compounds play a key role as olfactory cues for arthropod vectors such as mosquitoes, sand flies, and ticks, which act in the transmission of pathogens to many animal species, including humans. Some VOCs may influence arthropod behaviour, e.g., host preference and oviposition site selection for gravid females. Furthermore, deadly vector-borne pathogens such as Plasmodium falciparum and Leishmania infantum are suggested to manipulate the VOCs profile of the host to make them more attractive to mosquitoes and sand fly vectors, respectively. Under the above circumstances, studies on these compounds have demonstrated their potential usefulness for investigating the behavioural response of mosquitoes, sand flies, and ticks toward their vertebrate hosts, as well as potential tools for diagnosis of vector-borne diseases (VBDs). Herein, we provide an account for scientific data available on VOCs to study the host seeking behaviour of arthropod vectors, and their usefulness as attractants, repellents, or tools for an early diagnosis of VBDs.
摘要：
挥发性有机化合物（VOC）是作为细胞代谢产物排放的化学物质，它反映了任何生物体的生理和病理状况。这些化合物对节肢动物媒介如蚊子的嗅觉线索起着关键作用，沙蝇,和蜱,它在病原体向许多动物物种的传播中起作用，包括人类。一些挥发性有机化合物可能会影响节肢动物的行为，例如，妊娠雌性的寄主偏好和产卵位点选择。此外，致命的媒介传播病原体，如恶性疟原虫和婴儿利什曼原虫被建议操纵宿主的挥发性有机化合物谱，使它们对蚊子和沙蝇媒介更具吸引力，分别。在上述情况下,对这些化合物的研究已经证明了它们对调查蚊子的行为反应的潜在有用性，沙蝇,朝向它们的脊椎动物寄主，以及诊断媒介传播疾病（VBD）的潜在工具。在这里，我们提供了一份关于挥发性有机化合物的科学数据，以研究节肢动物媒介的宿主寻找行为，以及它们作为引诱剂的有用性，驱虫剂,或VBD的早期诊断工具。
