Abstract：
Haematopoietic stem cell collection from paediatric donors is a common and life-saving practice, as evidenced by the fact that there is a growing annual number of cases of transplants from minor donors among SFGM-TC centers over the last decade. Still, medical use of human tissue from a healthy and underage donor requires proper regulations and medical management. The guidelines below aim at underlining the importance of pondering the legal, medical and ethical aspects of using stem cells from healthy paediatric donors and stress out the importance of obtaining informed consent at the time of assessing HLA compatibility. Combined medical and psychological assessments are required before the donation, as well as one month later and one year later to ensure of the child\'s physical and mental wellbeing. Bone marrow harvest under general anaesthetics remains the preferred method of collection for children. Peripheral blood stem cell collection should only be considered for children who will not require a central venous access for collection. We aim at offering guidelines centered on the healthy child donating stem cells and his/her wellbeing, and these should be regularly reviewed as medical practices evolve.
摘要：
从儿科捐献者中收集造血干细胞是一种常见的挽救生命的做法，在过去的十年中，SFGM-TC中心的未成年人捐赠者移植病例的数量每年都在增加。尽管如此，从健康和未成年捐赠者的人体组织的医疗使用需要适当的法规和医疗管理。以下准则旨在强调思考法律的重要性，使用健康儿科供体干细胞的医学和伦理方面，并强调在评估HLA相容性时获得知情同意的重要性。捐赠前需要进行综合医疗和心理评估，以及一个月后和一年后，以确保孩子的身心健康。全身麻醉下的骨髓收获仍然是儿童的首选收集方法。外周血干细胞收集只应考虑不需要中心静脉途径收集的儿童。我们的目标是提供以健康儿童捐赠干细胞和他/她的健康为中心的指南，这些应该随着医疗实践的发展定期审查。
