UNASSIGNED: We conducted a retrospective, multicentric study including all consecutive patients undergoing any urological surgery with preoperative urine culture. The primary outcome was the occurrence of a UTI or surgical site infection occurring within 30 days after surgery.
UNASSIGNED: From 2016 to 2023, in 10 centers, 2389 patients were included with 838 (35%) positive urine cultures (mono-/bi-/polymicrobial). Postoperative infections occurred in 106 cases (4.4%), of which 44 had negative urine cultures (41%), 42 had positive mono-/bimicrobial urine cultures (40%), and 20 had polymicrobial urine cultures (19%). In multivariable analysis, UTI during the previous 12 months of surgery (odds ratio [OR] 3.43; 95% CI 2.07-5.66; P < .001), monomicrobial/bimicrobial preoperative urine culture (OR 3.68; 95% CI 1.57-8.42; P = .002), polymicrobial preoperative urine culture (OR 2.85; 95% CI 1.52-5.14; P < .001), and operative time (OR 1.09; 95% CI 1.04-1.15; P < .001) were independent associated factors for postoperative febrile infections.
UNASSIGNED: Positive urine culture, including preoperative polymicrobial urine culture, prior to urological surgery was associated with postoperative infection. Additionally, patients experiencing infectious complications also had a higher incidence of other complications. The effectiveness of systematic preventive antibiotic therapy for a positive urine culture has not been conclusively established.
■我们进行了回顾,多中心研究,包括所有连续接受泌尿外科手术的患者,术前尿液培养。主要结果是术后30天内发生尿路感染或手术部位感染。
■从2016年到2023年,在10个中心,2389名患者被纳入838(35%)阳性尿培养物(单/双/多微生物)。术后感染106例(4.4%),其中44例尿液培养阴性(41%),42具有阳性单/双微生物尿培养物(40%),20具有多微生物尿培养物(19%)。在多变量分析中,手术前12个月尿路感染(OR3.43;CI952.07-5.66;P<.001),单抗菌/双抗菌术前尿液培养(OR3.68;CI951.57-8.42;P0.02),多菌术前尿培养(OR2.85;CI951.52-5.14;P<.001),手术时间(OR1.09;CI951.04-1.15;P<.001)是术后发热感染的独立相关因素。
■尿培养阳性,包括术前微生物尿液培养,泌尿外科手术前与术后感染有关.此外,感染并发症患者的其他并发症发生率也较高.尚未确定对尿液培养阳性进行系统预防性抗生素治疗的有效性。