Abstract：
BACKGROUND: Postoperative wound infection after spinal surgery might be a challenge to manage. A wide range of procedures have been described for managing infected spinal wounds. An increasingly common procedure in the management of surgical site infections (SSI) is negative pressure wound therapy (NPWT), also known as vacuum-assisted closure. As there is a paucity of clear clinical advice the present investigation aims to update current evidence on the use of NPWT to manage postoperative SSI occurring after instrumented spine surgery.
METHODS: This systematic review was conducted according to the preferred reporting Items for systematic reviews and meta-analyses: the 2020 PRISMA statement. In January 2024, the following databases were accessed: PubMed, Web of Science, and Google Scholar. No time constraint was set for the search. All the clinical studies investigating the unique use of NPWT in treating postoperative spinal wound infections were accessed.
RESULTS: A total of 381 patients were included in the present study. Of them 52.5% (200 of 381 patients) were women. The mean age was 52.2 ± 15.2 years. The average length of the NPWT was 21.2 days (range 7-90 days).
CONCLUSIONS: NPWT could be a valuable adjuvant therapy for the management of SSI after spine surgery. Additional high-quality investigations are required to assess the efficacy and safety of NPWT in SSI after spine surgery, especially if combined with contraindications or risk factors, such as the presence of intraoperative CSF leak.
METHODS: Level IV, Systematic review.
METHODS: This systematic review was conducted according to the preferred reporting Items for systematic reviews and meta-analyses: the 2020 PRISMA statement. In January 2024, the following databases were accessed: PubMed, Web of Science, and Google Scholar. No time constraint was set for the search. All the clinical studies investigating the unique use of NPWT in treating postoperative spinal wound infections were accessed.
RESULTS: A total of 381 patients were included in the present study. Of them 52.5% (200 of 381 patients) were women. The mean age was 52.2 ± 15.2 years. The average length of the NPWT was 21.2 days (range 7-90 days).
CONCLUSIONS: NPWT could be a valuable adjuvant therapy for the management of SSI after spine surgery. Additional high-quality investigations are required to assess the efficacy and safety of NPWT in SSI after spine surgery, especially if combined with contraindications or risk factors, such as the presence of intraoperative CSF leak.
METHODS: Level IV, Systematic review.
摘要：
背景：脊柱手术后伤口感染可能是一个挑战。已经描述了用于管理感染的脊柱伤口的各种程序。在手术部位感染（SSI）的管理中越来越常见的程序是负压伤口治疗（NPWT）。也称为真空辅助关闭。由于缺乏明确的临床建议，因此本研究旨在更新有关使用NPWT来管理器械脊柱手术后发生的术后SSI的现有证据。
方法：本系统评价是根据系统评价和荟萃分析的首选报告项目进行的：2020PRISMA声明。2024年1月，访问了以下数据库：PubMed，WebofScience,谷歌学者。没有为搜索设置时间约束。访问了所有研究NPWT在治疗术后脊柱伤口感染中的独特用途的临床研究。
结果：本研究共纳入381例患者。其中52.5%（381例患者中有200例）是女性。平均年龄为52.2±15.2岁。NPWT的平均长度为21.2天(范围为7-90天)。
结论：NPWT可能是治疗脊柱手术后SSI的一种有价值的辅助治疗方法。需要额外的高质量研究来评估NPWT在脊柱手术后SSI中的疗效和安全性。特别是如果结合禁忌症或危险因素，如术中脑脊液渗漏的存在。
方法：四级，系统审查。
方法：本系统评价是根据系统评价和荟萃分析的首选报告项目进行的：2020PRISMA声明。2024年1月，访问了以下数据库：PubMed，WebofScience,谷歌学者。没有为搜索设置时间约束。访问了所有研究NPWT在治疗术后脊柱伤口感染中的独特用途的临床研究。
结果：本研究共纳入381例患者。其中52.5%（381例患者中有200例）是女性。平均年龄为52.2±15.2岁。NPWT的平均长度为21.2天(范围为7-90天)。
结论：NPWT可能是治疗脊柱手术后SSI的一种有价值的辅助治疗方法。需要额外的高质量研究来评估NPWT在脊柱手术后SSI中的疗效和安全性。特别是如果结合禁忌症或危险因素，如术中脑脊液渗漏的存在。
方法：四级，系统审查。
