关键词: Mycobacterium tuberculosis clivus cranial base nose and paranasal sinuses skull base malignancy skull base osteomyelitis small round blue cells

Mesh : Humans Mycobacterium tuberculosis / isolation & purification Skull Base / microbiology pathology Granuloma / microbiology diagnosis pathology United States Male Tuberculosis / diagnosis microbiology drug therapy Diagnosis, Differential Biopsy Antitubercular Agents / therapeutic use Female Middle Aged Tomography, X-Ray Computed

来  源:   DOI:10.1002/lary.31496

Abstract:
The differential for an ill-defined, bone-destructive, granulomatous lesion of the skull base includes malignancy, as well as autoimmune and infectious processes. Suspicion for tuberculosis of the skull base in high-risk patients is particularly necessary given the difficulty to culture on standard cultures, need for specific and prolonged antibiotic therapy, and dire morbidity if not diagnosed and treated in a timely manner. Repeat biopsies and cultures were necessary to diagnose this case of Mycobacterium tuberculosis of the skull base after initial biopsy was non-diagnostic. Laryngoscope, 134:4023-4027, 2024.
摘要:
定义不明确的差异,骨骼破坏性,颅底肉芽肿性病变包括恶性肿瘤,以及自身免疫和感染过程。鉴于在标准培养上难以培养,高危患者对颅底结核的怀疑尤其必要,需要特定和长期的抗生素治疗,和可怕的发病率,如果不及时诊断和治疗。在初次活检无法诊断后,必须进行重复活检和培养才能诊断颅底结核分枝杆菌。喉镜,2024.
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