{Reference Type}: Case Reports {Title}: Granulomatous Inflammation of the Skull Base: A Rare Case of Mycobacterium tuberculosis in the United States. {Author}: Kandahari N;Johnson SM;Thorp BD; {Journal}: Laryngoscope {Volume}: 134 {Issue}: 9 {Year}: 2024 Sep 16 {Factor}: 2.97 {DOI}: 10.1002/lary.31496 {Abstract}: The differential for an ill-defined, bone-destructive, granulomatous lesion of the skull base includes malignancy, as well as autoimmune and infectious processes. Suspicion for tuberculosis of the skull base in high-risk patients is particularly necessary given the difficulty to culture on standard cultures, need for specific and prolonged antibiotic therapy, and dire morbidity if not diagnosed and treated in a timely manner. Repeat biopsies and cultures were necessary to diagnose this case of Mycobacterium tuberculosis of the skull base after initial biopsy was non-diagnostic. Laryngoscope, 134:4023-4027, 2024.