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Abstract：
BACKGROUND: To evaluate differences in log MAR best-corrected visual acuity (BCVA) improvement and postoperative central foveal thickness (CFT) and choroidal thickness (CT) changes between conventional phacoemulsification surgery (CPS) and femtosecond laser-assisted cataract surgery (FLACS) for high-myopia cataracts.
METHODS: This was a retrospective and observational study. One hundred and two eyes of 102 patients with high-myopia cataracts were examined. CPS was performed in 54 eyes, and FLACS was performed in 48 eyes. All eyes underwent logMAR BCVA, CFT and CT of three different sectors preoperatively and one week and six months postoperatively.
RESULTS: The logMAR BCVA improved significantly after surgery in both groups (both P < 0.001), but no difference was observed in BCVA improvement between the groups (P = 0.554). Moreover, no significant differences were reflected in the changes in CFT, nasal 1 mm CT or temporal 1 mm CT between the two groups, and only subfoveal choroidal thickness (SFCT) in the CPS group decreased significantly compared with that in the FLACS group at any postoperative time (P = 0.003 and 0.026). AL, preoperative logMAR BCVA, and CT of the three regions exhibited a notable correlation with postoperative BCVA (all P < 0.05) according to univariate logistic regression analysis. However, only the AL, preoperative logMAR BCVA and SFCT remained significant in the multivariate model. Postoperative logMAR BCVA revealed a positive correlation with AL and preoperative logMAR BCVA but a negative correlation with SFCT.
CONCLUSIONS: FLACS was not superior to CPS in improving BCVA but had less impact on SFCT in the treatment of high-myopia cataracts. Eyes with a longer AL, worse preoperative logMAR BCVA and thinner SFCT had a high risk of worse postoperative BCVA.
METHODS: This was a retrospective and observational study. One hundred and two eyes of 102 patients with high-myopia cataracts were examined. CPS was performed in 54 eyes, and FLACS was performed in 48 eyes. All eyes underwent logMAR BCVA, CFT and CT of three different sectors preoperatively and one week and six months postoperatively.
RESULTS: The logMAR BCVA improved significantly after surgery in both groups (both P < 0.001), but no difference was observed in BCVA improvement between the groups (P = 0.554). Moreover, no significant differences were reflected in the changes in CFT, nasal 1 mm CT or temporal 1 mm CT between the two groups, and only subfoveal choroidal thickness (SFCT) in the CPS group decreased significantly compared with that in the FLACS group at any postoperative time (P = 0.003 and 0.026). AL, preoperative logMAR BCVA, and CT of the three regions exhibited a notable correlation with postoperative BCVA (all P < 0.05) according to univariate logistic regression analysis. However, only the AL, preoperative logMAR BCVA and SFCT remained significant in the multivariate model. Postoperative logMAR BCVA revealed a positive correlation with AL and preoperative logMAR BCVA but a negative correlation with SFCT.
CONCLUSIONS: FLACS was not superior to CPS in improving BCVA but had less impact on SFCT in the treatment of high-myopia cataracts. Eyes with a longer AL, worse preoperative logMAR BCVA and thinner SFCT had a high risk of worse postoperative BCVA.
摘要：
背景：评估高度近视白内障的常规超声乳化手术（CPS）和飞秒激光辅助白内障手术（FLACS）在logMAR最佳矫正视力（BCVA）改善以及术后中央凹厚度（CFT）和脉络膜厚度（CT）变化方面的差异。
方法：这是一项回顾性观察性研究。检查了102例高度近视白内障患者的一百零二只眼。在54只眼中进行了CPS，48只眼进行FLACS。所有的眼睛都接受了logmarBCVA,术前和术后一周和六个月三个不同部门的CFT和CT。
结果：两组手术后logMARBCVA均有明显改善（均P<0.001），但两组间BCVA改善无差异(P=0.554).此外，CFT的变化没有显著差异，两组之间的鼻腔1毫米CT或颞部1毫米CT，与FLACS组相比，CPS组仅中央凹下脉络膜厚度（SFCT）在术后任何时间显着降低（P=0.003和0.026）。AL,术前logMARBCVA，单因素logistic回归分析显示,3个区域的CT与术后BCVA呈显著相关(均P<0.05)。然而,只有AL,术前logMARBCVA和SFCT在多变量模型中仍然显著.术后logMARBCVA与AL和术前logMARBCVA呈正相关，与SFCT呈负相关。
结论：FLACS在改善BCVA方面并不优于CPS，但对SFCT治疗高度近视白内障的影响较小。眼睛有一个较长的AL，术前logMAR较差的BCVA和较薄的SFCT术后BCVA较差的风险较高.
方法：这是一项回顾性观察性研究。检查了102例高度近视白内障患者的一百零二只眼。在54只眼中进行了CPS，48只眼进行FLACS。所有的眼睛都接受了logmarBCVA,术前和术后一周和六个月三个不同部门的CFT和CT。
结果：两组手术后logMARBCVA均有明显改善（均P<0.001），但两组间BCVA改善无差异(P=0.554).此外，CFT的变化没有显著差异，两组之间的鼻腔1毫米CT或颞部1毫米CT，与FLACS组相比，CPS组仅中央凹下脉络膜厚度（SFCT）在术后任何时间显着降低（P=0.003和0.026）。AL,术前logMARBCVA，单因素logistic回归分析显示,3个区域的CT与术后BCVA呈显著相关(均P<0.05)。然而,只有AL,术前logMARBCVA和SFCT在多变量模型中仍然显著.术后logMARBCVA与AL和术前logMARBCVA呈正相关，与SFCT呈负相关。
结论：FLACS在改善BCVA方面并不优于CPS，但对SFCT治疗高度近视白内障的影响较小。眼睛有一个较长的AL，术前logMAR较差的BCVA和较薄的SFCT术后BCVA较差的风险较高.
