METHODS: This is a systematic review and meta-analysis in which three international databases including Medline through PubMed, Scopus and Web of Science on November 2023 were searched. To screen and select relevant studies, retrieved articles were entered into Endnote software. The required information was extracted from the full text of the retrieved articles by the authors. Effect measures in this study was the intra-operative, in-hospital, and 90-day and overall MR following TPE. All analyzes are performed using Stata software version 16 (Stata Corp, College Station, TX).
RESULTS: In this systematic review, 1751 primary studies retrieved, of which 98 articles (5343 cases) entered into this systematic review. The overall mortality rate was 30.57% in colorectal cancers, 25.5% in gynecological cancers and 12.42% in Miscellaneous. The highest rate of mortality is related to the overall mortality rate of colorectal cancers. The MR in open surgeries was higher than in minimally invasive surgeries, and also in primary advanced cancers, it was higher than in recurrent cancers.
CONCLUSIONS: In conclusion, it can be said that performing TPE in a specialized surgical center with careful patient eligibility evaluation is a viable option for advanced malignancies of the pelvic organs.
方法:这是一项系统综述和荟萃分析,其中包括Medline通过PubMed,搜索了2023年11月的Scopus和WebofScience。要筛选和选择相关研究,检索到的文章被输入到Endnote软件。所需信息是从作者检索的文章全文中提取的。这项研究的效果指标是术中,在医院,TPE后90天和整体MR。所有分析均使用Stata软件版本16(StataCorp,学院站,TX)。
结果:在本系统综述中,检索到1751项主要研究,其中98篇文章(5343例)进入了这项系统审查。大肠癌的总死亡率为30.57%,妇科癌症占25.5%,杂项癌症占12.42%。最高的死亡率与结直肠癌的总死亡率有关。开放手术的MR高于微创手术,在原发性晚期癌症中,它高于复发性癌症。
结论:结论:可以说,对于盆腔器官的晚期恶性肿瘤,在专门的外科中心进行TPE并仔细评估患者的合格性,是一种可行的选择.